{"id":"W4282010314","doi":"10.1101/2022.06.10.495605","title":"Global Profiling of c-Jun and JunB transcription factor binding sites in an ALK+ ALCL cell line","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"University of Alberta","keywords":"JUNB; Anaplastic lymphoma kinase; Anaplastic large-cell lymphoma; c-jun; Cancer research; Transcription factor; Molecular biology; Cell growth; Biology; Chromatin immunoprecipitation; Chemistry; Gene expression; Gene; Genetics; Lymphoma; Promoter; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000104811,0.0002189129,0.0002614135,0.0005167629,0.000295991,0.0002561991,0.0001649864,0.0002053753,0.0008848854],"category_scores_gemma":[0.00009745866,0.0001275217,0.0002357439,0.0006113432,0.0001567477,0.00008569595,0.0001662875,0.0003315304,0.0004312587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000185603,"about_ca_system_score_gemma":0.0001475375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001225494,"about_ca_topic_score_gemma":0.002405804,"domain_scores_codex":[0.9998161,0.00001277845,0.000007987386,0.00005112149,0.00008005212,0.00003190019],"domain_scores_gemma":[0.9998847,0.00002457198,0.00002080171,0.00001218514,0.00003191705,0.0000257043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004352308,0.00001188205,0.0005761579,0.00001633034,0.000004905502,0.00001470878,0.00001264848,0.0000347324,0.9987106,0.00001294316,0.00002414654,0.0005374568],"study_design_scores_gemma":[0.00003074096,0.0003814055,0.1342123,0.000008864396,0.0000680157,0.0005091617,0.0001990025,0.004389651,0.8561361,0.0001002119,0.00394581,0.00001884074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876758,0.001680392,0.004548254,0.00006254598,0.00001770729,0.0000450979,0.004484514,0.0001032903,0.001382425],"genre_scores_gemma":[0.9785116,0.0009245168,0.007124327,0.0001191282,0.00001349597,0.000116665,0.009976505,0.00004471662,0.003169139],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001225494,"threshold_uncertainty_score":0.002960265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02539934170942106,"score_gpt":0.2603755744009625,"score_spread":0.2349762326915415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}