{"id":"W4282021509","doi":"10.1182/bloodadvances.2021006654","title":"Genomic characterization of lymphomas in patients with inborn errors of immunity","year":2022,"lang":"en","type":"article","venue":"Blood Advances","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Health Services","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Biology; Lymphoma; Germline; Cancer research; Genome; Genetics; Germline mutation; PTEN; Mutation; Gene; Immunology; PI3K/AKT/mTOR pathway","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001129446,0.0001921668,0.0001951381,0.0009703037,0.000150542,0.0002860525,0.0001339627,0.0002066332,0.001104277],"category_scores_gemma":[0.0004362152,0.00007041961,0.000131801,0.000488284,0.0001420511,0.000122193,0.0002945834,0.0001935746,0.0001608179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001057537,"about_ca_system_score_gemma":0.00007098257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004028261,"about_ca_topic_score_gemma":0.0004303443,"domain_scores_codex":[0.999869,0.0000213722,0.00001243528,0.00004392151,0.00002834577,0.00002495842],"domain_scores_gemma":[0.9998115,0.00005643442,0.00005998808,0.00001667101,0.00002449958,0.00003088584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004189495,0.00004424535,0.7247258,0.0001021554,0.0001012262,0.005025122,0.0003773116,0.0004441405,0.2284565,0.0003216937,0.0004925372,0.03949032],"study_design_scores_gemma":[0.00001462764,0.0001717619,0.944132,0.00002482847,0.0001127233,0.02248465,0.0004031533,0.0008221825,0.02696284,0.0002786557,0.004584402,0.000008208984],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959559,0.001063575,0.001365196,0.00005202302,0.000003617162,0.00001264131,0.0006511011,0.00003273637,0.0008631905],"genre_scores_gemma":[0.9979841,0.0003732817,0.0006639379,0.00003880862,0.000006751212,0.000007556356,0.0007410673,0.000007173693,0.0001772144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001104277,"threshold_uncertainty_score":0.003694117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003045036758666962,"score_gpt":0.1787598235237056,"score_spread":0.1757147867650386,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}