{"id":"W4282052404","doi":"10.1101/2022.06.10.495573","title":"Human sperm TMEM95 binds eggs and facilitates membrane fusion","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"SLAC National Accelerator Laboratory; Biological and Environmental Research; Echo Foundation; Basic Energy Sciences; National Institute of Child Health and Human Development; Japan Society for the Promotion of Science; Office of Science; Buck Institute for Research on Aging; National Science Foundation; Damon Runyon Cancer Research Foundation; Virginia and D.K. Ludwig Fund for Cancer Research; U.S. Department of Energy; National Institutes of Health","keywords":"Sperm; Biology; Lipid bilayer fusion; Sterility; Hamster; Cell biology; Monoclonal antibody; Genetics; Molecular biology; Antibody; Membrane","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001323429,0.0002263135,0.0001616674,0.0001579314,0.0001066162,0.0002194529,0.0002123856,0.0002965488,0.002425439],"category_scores_gemma":[0.0002170938,0.0001163231,0.0002495592,0.0001005256,0.0001143946,0.0001355539,0.0002283971,0.0002808363,0.0005213778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002574216,"about_ca_system_score_gemma":0.00008929134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006364163,"about_ca_topic_score_gemma":0.0004986526,"domain_scores_codex":[0.9998535,0.00002539919,0.00001364295,0.00003142885,0.00004807333,0.00002807231],"domain_scores_gemma":[0.9999256,0.00002240932,0.00001942615,0.000009538985,0.00001114445,0.00001197676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000551508,0.00001110308,0.0006484238,0.00003934686,0.000008987739,0.00009216592,0.0000168744,0.00006905983,0.9975718,0.0001545723,0.00006855228,0.001263906],"study_design_scores_gemma":[0.00001795194,0.000119071,0.005671867,0.000007918428,0.00001242053,0.0006730975,0.00002794063,0.0008852844,0.989455,0.00003985722,0.003086087,0.000003532479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933236,0.001819166,0.003052258,0.00009218985,0.00001571667,0.00001376525,0.0001498361,0.00005907808,0.00147425],"genre_scores_gemma":[0.9954053,0.0003969857,0.001869524,0.00005868405,0.000003466041,0.000007743869,0.0003240231,0.000008199539,0.001926145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002425439,"threshold_uncertainty_score":0.008113861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01773458804758227,"score_gpt":0.2478656868535956,"score_spread":0.2301310988060133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}