{"id":"W4282572324","doi":"10.1128/spectrum.00412-22","title":"Comprehensive Assessment of Functional Effects of Commonly Used Sugar Substitute Sweeteners on <i>Ex Vivo</i> Human Gut Microbiome","year":2022,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Biochemical Analysis and Sensing Techniques","field":"Nursing","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Microbiome; Ex vivo; Gut microbiome; Biology; Sugar; In vivo; Biotechnology; Medicine; Computational biology; Bioinformatics; Food science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004558483,0.0005427579,0.000455804,0.0005580761,0.0002484252,0.0004434131,0.0001289637,0.0003466448,0.001438539],"category_scores_gemma":[0.0005286991,0.0001527994,0.0005629358,0.0005826892,0.0002350468,0.0003988316,0.0005380141,0.0004249391,0.0002603328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001110971,"about_ca_system_score_gemma":0.0002713103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004940277,"about_ca_topic_score_gemma":0.001038774,"domain_scores_codex":[0.9996775,0.00008184035,0.00002792205,0.00007168655,0.00009332122,0.00004778989],"domain_scores_gemma":[0.9997789,0.00003970819,0.0000614958,0.00001930021,0.0000669265,0.00003361305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005863957,0.00006357632,0.004987753,0.0003194379,0.00005351703,0.00005354613,0.0000829629,0.0001129157,0.9826332,0.0000683172,0.0001215259,0.01091692],"study_design_scores_gemma":[0.00001697643,0.002557371,0.1118509,0.0001416019,0.000326148,0.0003251883,0.0007877325,0.0007918359,0.8750665,0.0002566232,0.007820825,0.00005831011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872116,0.006225713,0.002643886,0.0001528662,0.00008465184,0.00005258303,0.001863282,0.00004050074,0.00172489],"genre_scores_gemma":[0.980963,0.006893686,0.007500959,0.0004194514,0.00004194788,0.0001123848,0.002122197,0.00004185317,0.001904486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001438539,"threshold_uncertainty_score":0.00481236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01448428982238654,"score_gpt":0.2640284252370242,"score_spread":0.2495441354146377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}