{"id":"W4282583538","doi":"10.1093/nar/gkac485","title":"TWIST1 methylation by SETD6 selectively antagonizes LINC-PINT expression in glioma","year":2022,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"National Cancer Institute; Israel Science Foundation; Israel Cancer Association; Israel Cancer Research Fund; National Science Foundation","keywords":"Biology; Methylation; Glioma; DNA methylation; Cell biology; Gene expression; Cancer research; Genetics; Molecular biology; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009843628,0.0002476179,0.0002426387,0.0001892453,0.0001444686,0.000213418,0.0002287993,0.0001694788,0.001931193],"category_scores_gemma":[0.00014157,0.0001400134,0.0002027604,0.0001016751,0.0002252769,0.0001033376,0.0002440554,0.000374706,0.0003572275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002873252,"about_ca_system_score_gemma":0.0002083335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008555288,"about_ca_topic_score_gemma":0.002135623,"domain_scores_codex":[0.999898,0.00001695464,0.000008681279,0.00001924652,0.00002842461,0.00002874986],"domain_scores_gemma":[0.9999219,0.00001215412,0.00002085814,0.000008998213,0.000006057302,0.00002992767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001302652,0.00001603979,0.0002883119,0.00003525701,0.000007151721,0.00004283244,0.00001027429,0.0001285028,0.998135,0.00008053963,0.00004513394,0.001080595],"study_design_scores_gemma":[0.0000163155,0.0002261476,0.005423271,0.000003735049,0.00001396891,0.0002070538,0.00002264077,0.0009685826,0.991511,0.00004520666,0.001557672,0.000004343485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948159,0.001492149,0.001645396,0.0000957899,0.00003195392,0.00001513066,0.000262856,0.0001088681,0.001531993],"genre_scores_gemma":[0.9979191,0.0003903512,0.0004330634,0.00003769579,0.000003532249,0.00000884962,0.0002499716,0.00001677253,0.0009405032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001931193,"threshold_uncertainty_score":0.006460488,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0318821290327901,"score_gpt":0.3475962355593334,"score_spread":0.3157141065265434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}