{"id":"W4282587412","doi":"10.3390/molecules27123684","title":"Tripeptide IRW Protects MC3T3-E1 Cells against Ang II Stress in an AT2R Dependent Manner","year":2022,"lang":"en","type":"article","venue":"Molecules","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Egg Farmers of Canada","keywords":"RANKL; Chemistry; Angiotensin II; Alkaline phosphatase; Receptor; Activator (genetics); Osteoblast; Cell biology; Biochemistry; Biology; In vitro; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000109651,0.0003731353,0.0005338159,0.0001851329,0.0001328552,0.0002488585,0.00020347,0.0003163338,0.001390161],"category_scores_gemma":[0.00007070909,0.0001129404,0.0003366123,0.0001332334,0.0002001648,0.0001660486,0.0001406574,0.0008042514,0.0003642765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001204767,"about_ca_system_score_gemma":0.0001653097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009091153,"about_ca_topic_score_gemma":0.001203816,"domain_scores_codex":[0.9998972,0.00001122857,0.000009919714,0.00002064546,0.00003219028,0.00002880549],"domain_scores_gemma":[0.9999517,0.000006283403,0.00001493924,0.000005936651,0.000006963436,0.00001422128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002573995,0.00007390187,0.00008430664,0.00003428189,0.000007741123,0.00005944131,0.000009659909,0.00003095705,0.9985716,0.00002043782,0.00003328176,0.0008170161],"study_design_scores_gemma":[0.00009373441,0.002799319,0.007984647,0.000009107227,0.00005063106,0.0004179209,0.00007501964,0.0005196441,0.9850978,0.00006010632,0.002880245,0.00001187055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946697,0.00250694,0.001175587,0.000132617,0.00005240365,0.00002482376,0.0004901191,0.00006044418,0.0008873128],"genre_scores_gemma":[0.9935617,0.001471516,0.001546876,0.0001503162,0.00003019463,0.000048744,0.0008367573,0.00002094697,0.002332901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001390161,"threshold_uncertainty_score":0.004650533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007318775890209206,"score_gpt":0.2223165084868737,"score_spread":0.2149977325966645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}