{"id":"W4282823323","doi":"10.3390/molecules27123807","title":"Accum™ Technology: A Novel Conjugable Primer for Onco-Immunotherapy","year":2022,"lang":"en","type":"review","venue":"Molecules","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Endosome; Immunogenicity; Intracellular; Epitope; Antigen; Cell biology; Cancer immunotherapy; Immunotherapy; Cancer research; Chemistry; Biology; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005210584,0.0008667532,0.002373386,0.0008775691,0.0007470769,0.00005272169,0.001384472,0.001246042,0.003037016],"category_scores_gemma":[0.0002167108,0.0007499015,0.001159616,0.0006920493,0.0004388166,0.00008067786,0.000297358,0.001126794,0.0004589056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002282025,"about_ca_system_score_gemma":0.0007573706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003055527,"about_ca_topic_score_gemma":0.000001579593,"domain_scores_codex":[0.9968431,0.0003666441,0.0009739228,0.0008355584,0.00007642412,0.0009043548],"domain_scores_gemma":[0.9972004,0.0008389326,0.0006656532,0.001202365,0.00007396291,0.00001873148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003495629,0.0003709017,3.937889e-7,0.001320314,0.002285314,0.000005968057,0.0000773668,4.186714e-7,0.01272727,0.0022142,0.004314742,0.9763336],"study_design_scores_gemma":[0.001920986,0.0005715851,4.806751e-7,0.001158142,0.0004618835,0.000331668,0.00007192408,2.596957e-7,0.002530256,0.0001030182,0.9920389,0.0008108776],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001247091,0.9929923,0.001308223,0.0000977681,0.001411161,0.002349684,0.0005123068,0.0003380957,0.0009779403],"genre_scores_gemma":[0.000003803667,0.9770635,0.0007864615,0.0002667666,0.00003993778,0.002833806,0.001158469,0.0002393504,0.01760784],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9877242,"threshold_uncertainty_score":0.9994952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05342048330908922,"score_gpt":0.3312879645398795,"score_spread":0.2778674812307902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}