{"id":"W4282826809","doi":"10.1038/s41386-022-01354-w","title":"The neurobiological markers of acute alcohol’s subjective effects in humans","year":2022,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada","keywords":"Ingestion; Sedation; Stimulation; GABAergic; Alcohol; Placebo; Ethanol; Psychology; Transcranial magnetic stimulation; Craving; Medicine; Pharmacology; Anesthesia; Internal medicine; Endocrinology; Neuroscience; Inhibitory postsynaptic potential; Chemistry; Addiction; Biochemistry; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001280216,0.0001629502,0.000145796,0.0003213832,0.0002687269,0.0003395374,0.00008445336,0.0001799913,0.00112217],"category_scores_gemma":[0.0003805493,0.0001363832,0.00008124475,0.0001511841,0.0004196141,0.0001643871,0.0001609758,0.0002444124,0.0001073592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002832029,"about_ca_system_score_gemma":0.0001761494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005638373,"about_ca_topic_score_gemma":0.01038005,"domain_scores_codex":[0.9999589,0.00001484137,0.000003023682,0.000008751668,0.000008547901,0.000006010862],"domain_scores_gemma":[0.9997424,0.00003045235,0.000107522,0.00002252102,0.00005153722,0.00004564242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009444289,0.0008460785,0.6505017,0.0003558295,0.0005500127,0.001003043,0.001010197,0.0003656107,0.274911,0.00146879,0.0005071032,0.05903638],"study_design_scores_gemma":[0.000009338997,0.0004134878,0.9930213,0.000007055606,0.00002851921,0.0002156996,0.0002042707,0.0001245694,0.005428497,0.0001497946,0.0003912797,0.000006253497],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959348,0.001575024,0.0003794414,0.00006147513,0.00001130528,0.00001540498,0.0001551803,0.000004770221,0.001862583],"genre_scores_gemma":[0.9985164,0.0007754173,0.0001789513,0.00003317854,0.000006674284,0.000004074619,0.00008428452,0.00000131964,0.0003998836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005638373,"threshold_uncertainty_score":0.0112111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0248926344226598,"score_gpt":0.3284538378883035,"score_spread":0.3035612034656436,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}