{"id":"W4282831736","doi":"10.2217/imt-2021-0250","title":"No Association Between BMI and Immunotoxicity or Clinical Outcomes for Immune Checkpoint Inhibitors","year":2022,"lang":"en","type":"article","venue":"Immunotherapy","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kingston Health Sciences Centre","funders":"","keywords":"Medicine; Internal medicine; Adverse effect; Oncology; Immune system; Immune checkpoint; Immunotherapy; Retrospective cohort study; Cancer; Population; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001659215,0.0001742616,0.0003696546,0.0004204918,0.0002274904,0.0004843225,0.0002382053,0.000316098,0.001941784],"category_scores_gemma":[0.006419268,0.000138659,0.0004912773,0.0005401562,0.0002697275,0.0003152213,0.000300817,0.000620315,0.0001918942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000198497,"about_ca_system_score_gemma":0.0003564257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003622891,"about_ca_topic_score_gemma":0.0006429578,"domain_scores_codex":[0.9993424,0.0002083086,0.00008775136,0.0001192111,0.000163868,0.00007833431],"domain_scores_gemma":[0.9911204,0.002943202,0.003994298,0.0004954849,0.0005934654,0.0008530812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006360532,0.00001921546,0.9975418,0.00001377174,0.00009471223,0.00003702503,0.000007953759,0.0000331683,0.0002989651,0.00001240675,0.00003250555,0.001272481],"study_design_scores_gemma":[0.00002100219,0.0004481707,0.9985885,0.000007667559,0.0001036108,0.0003358609,0.0000254966,0.0001295323,0.000122822,0.00003417902,0.0001797053,0.000003403387],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978149,0.0009300961,0.000191537,0.00007041216,0.00001915452,0.000009488613,0.0002210886,0.000003703017,0.0007396043],"genre_scores_gemma":[0.9995553,0.00008998085,0.0000647792,0.00003450573,0.00001560705,0.000004949909,0.0001683077,0.000001945197,0.00006456167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001941784,"threshold_uncertainty_score":0.008774877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03765313257344467,"score_gpt":0.3521172211629623,"score_spread":0.3144640885895177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}