{"id":"W4282831736","doi":"10.2217/imt-2021-0250","title":"No Association Between BMI and Immunotoxicity or Clinical Outcomes for Immune Checkpoint Inhibitors","year":2022,"lang":"en","type":"article","venue":"Immunotherapy","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kingston Health Sciences Centre","funders":"","keywords":"Medicine; Internal medicine; Adverse effect; Oncology; Immune system; Immune checkpoint; Immunotherapy; Retrospective cohort study; Cancer; Population; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002803065,0.0002992926,0.0008560474,0.0001357251,0.0005120058,0.00005712933,0.0002071127,0.0001953765,0.0006946473],"category_scores_gemma":[0.0003127747,0.0002383083,0.0007026693,0.0002629904,0.0001113664,0.0001179901,0.000098454,0.000509004,0.00001506453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006213278,"about_ca_system_score_gemma":0.0002550343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003256805,"about_ca_topic_score_gemma":0.000009765259,"domain_scores_codex":[0.9971675,0.0002202518,0.001234364,0.0004434993,0.0004875391,0.0004468135],"domain_scores_gemma":[0.9978349,0.0008638899,0.0005763704,0.0004912745,0.0001517614,0.0000818253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02482721,0.0009136664,0.7610055,0.0000993918,0.004612154,0.00001085436,0.0006951974,0.000001043547,0.09096732,0.00005058691,0.004102473,0.1127146],"study_design_scores_gemma":[0.01703297,0.002872381,0.6098418,0.00003958467,0.0001447084,0.00001940154,0.000199675,0.00003391568,0.003813365,0.00007625421,0.3655686,0.0003573086],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990419,0.002380161,0.0001455655,0.00308599,0.001563561,0.001771384,0.0001598717,0.0001521791,0.0003222908],"genre_scores_gemma":[0.966998,0.002502907,0.001676969,0.003908927,0.0008673767,0.0007689402,0.0002070336,0.0001510821,0.02291881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3614661,"threshold_uncertainty_score":0.9717929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03765313257344467,"score_gpt":0.3521172211629623,"score_spread":0.3144640885895177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}