{"id":"W4282838554","doi":"10.1158/1055-9965.epi-22-0043","title":"Does a Multiple Myeloma Polygenic Risk Score Predict Overall Survival of Patients with Myeloma?","year":2022,"lang":"en","type":"review","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Centre for Applied Research in Cancer Control","funders":"National Cancer Institute","keywords":"Multiple myeloma; Medicine; Internal medicine; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002317496,0.0004309276,0.0008568333,0.0008583296,0.0002727417,0.0008496519,0.0005634946,0.0008064689,0.001746736],"category_scores_gemma":[0.004827199,0.0002623191,0.003521728,0.002052926,0.0004026381,0.0005378833,0.0005425708,0.0009472968,0.0001541239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003497096,"about_ca_system_score_gemma":0.0004210506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003682066,"about_ca_topic_score_gemma":0.00446393,"domain_scores_codex":[0.9989935,0.0003930483,0.0001012193,0.0003238341,0.000101184,0.0000871891],"domain_scores_gemma":[0.9962687,0.001815704,0.001186778,0.0003397016,0.0002174476,0.0001714879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001143447,0.0000227762,0.9766771,0.0003643211,0.01102842,0.0000912094,0.00004875067,0.0009331522,0.0004191907,0.0001393432,0.0005316152,0.00860067],"study_design_scores_gemma":[0.0001282408,0.0001991253,0.9761364,0.0001702827,0.01671115,0.0003395538,0.00007619664,0.003407757,0.0002737349,0.00119758,0.001336161,0.00002370568],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9307697,0.06144413,0.002317782,0.001815244,0.0001234747,0.00002461251,0.002325089,0.00004310104,0.001136858],"genre_scores_gemma":[0.9966199,0.002310453,0.0003113999,0.0001262509,0.0000838302,0.000009736162,0.00044657,0.000005389721,0.00008635609],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.003682066,"threshold_uncertainty_score":0.01225626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08076212401473437,"score_gpt":0.3798568738281204,"score_spread":0.2990947498133861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}