{"id":"W4282841494","doi":"10.3389/fcimb.2022.883163","title":"Intestinal Microbial Composition of Children in a Randomized Controlled Trial of Probiotics to Treat Acute Gastroenteritis","year":2022,"lang":"en","type":"article","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre; London Health Sciences Centre; SickKids Foundation; Western University; University of Toronto; Dalhousie University; Centre Hospitalier Universitaire Sainte-Justine; Izaak Walton Killam Health Centre; Stollery Children's Hospital; Alberta Children's Hospital; Hospital for Sick Children; Université de Montréal; University of Alberta; Children's Hospital of Eastern Ontario; University of Calgary; University of Ottawa; Provincial Laboratory of Public Health","funders":"Canadian Institutes of Health Research; Alberta Children's Hospital Foundation; Children's Hospital Foundation; Calgary Laboratory Services","keywords":"Metagenomics; Gut flora; Microbiome; Placebo; Biology; Acute gastroenteritis; Medicine; Microbiology; Internal medicine; Physiology; Immunology; Bioinformatics; Virology; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003441367,0.001676057,0.005437498,0.000446219,0.0009709289,0.001532444,0.0008064417,0.002495744,0.005366482],"category_scores_gemma":[0.005303595,0.001186012,0.002740082,0.0005970704,0.001488887,0.00114101,0.0007728751,0.003022124,0.0006722852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001214549,"about_ca_system_score_gemma":0.002396814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002392529,"about_ca_topic_score_gemma":0.00473667,"domain_scores_codex":[0.9974322,0.001350477,0.0002969368,0.0003666949,0.0001747252,0.000379082],"domain_scores_gemma":[0.9976497,0.0005599225,0.0006390793,0.0001927189,0.0002436191,0.0007149302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9917914,0.002435913,0.001243267,0.0003568392,0.0009544173,0.00001800689,0.0000398103,0.00004209035,0.0005172846,0.00002024102,0.000185449,0.002395405],"study_design_scores_gemma":[0.9208184,0.06840539,0.008489223,0.00007737055,0.001285333,0.00001924927,0.00004924322,0.0001211813,0.0001951725,0.00007330943,0.0004480083,0.00001819917],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857927,0.004601681,0.0003004378,0.0005602066,0.000672522,0.006198492,0.00103963,0.00006304657,0.0007712732],"genre_scores_gemma":[0.9795783,0.00251024,0.001404034,0.0009171274,0.0005567521,0.01292074,0.0008471335,0.00001934545,0.001246245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005437498,"threshold_uncertainty_score":0.01819986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003031643603991681,"score_gpt":0.213187359850586,"score_spread":0.2101557162465943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}