{"id":"W4282914986","doi":"10.3389/fcimb.2022.852473","title":"Porcine Sapelovirus 3Cpro Inhibits the Production of Type I Interferon","year":2022,"lang":"en","type":"article","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"Fundamental Research Funds for the Central Universities; Natural Science Foundation of Hubei Province; National Natural Science Foundation of China","keywords":"Interferon; Biology; Interferon type I; IRF3; TANK-binding kinase 1; MDA5; Microbiology; Pathogen; TRIF; Virology; Gene; Kinase; Immunology; Cell biology; RNA interference; Innate immune system; RNA; Immune system; Protein kinase A; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001140718,0.0002997901,0.0002089255,0.000172901,0.0001002213,0.0002209969,0.0001351227,0.000284358,0.0008545186],"category_scores_gemma":[0.0001279018,0.00007549726,0.0003378047,0.00007754084,0.0001642138,0.0001776972,0.0001088671,0.0005176216,0.0002244883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001622446,"about_ca_system_score_gemma":0.0002057697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004467246,"about_ca_topic_score_gemma":0.0006229933,"domain_scores_codex":[0.9998678,0.00002379646,0.0000123831,0.00001904067,0.00003189846,0.00004499323],"domain_scores_gemma":[0.9999349,0.00001434371,0.00001346814,0.0000108008,0.00001003308,0.00001645063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001883146,0.00007588786,0.0002034781,0.00004586619,0.000006713268,0.00003376208,0.000007732092,0.00005359898,0.9973637,0.00005989916,0.00006773503,0.001893323],"study_design_scores_gemma":[0.0000336592,0.001343912,0.005401266,0.000008327797,0.0000167114,0.0002287924,0.00002346508,0.001121059,0.9893218,0.00005142788,0.002444881,0.00000468042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928668,0.001850549,0.00177179,0.0001155131,0.0000839305,0.00003263172,0.0001955752,0.00006110809,0.003022181],"genre_scores_gemma":[0.9953434,0.0006742531,0.001202336,0.0001072,0.00002113549,0.0000246755,0.0005285136,0.00001086533,0.002087648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008545186,"threshold_uncertainty_score":0.002858639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01474704926993214,"score_gpt":0.2552857340518154,"score_spread":0.2405386847818832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}