{"id":"W4282917982","doi":"10.1158/1538-7445.am2022-1694","title":"Abstract 1694: Cytotoxic conditions alter cell free DNA concentration and fragment size in cancer cells","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Cytotoxic T cell; Apoptosis; Colorectal cancer; Cancer; Cancer research; Cell cycle; Programmed cell death; Biomarker; Lung cancer; Cancer cell; Medicine; Biology; Molecular biology; Immunology; Pathology; In vitro; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001378344,0.0002679619,0.0001842692,0.000251052,0.000162617,0.0002042137,0.0001299811,0.0003194121,0.00322398],"category_scores_gemma":[0.0002283497,0.0001120371,0.000185897,0.0002232816,0.0002005612,0.0002271945,0.000128405,0.0003169224,0.0005472229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003154835,"about_ca_system_score_gemma":0.0001833472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007744664,"about_ca_topic_score_gemma":0.0005346939,"domain_scores_codex":[0.9998255,0.0000246753,0.00001583291,0.00005152848,0.00005865116,0.00002374694],"domain_scores_gemma":[0.9998332,0.00005511754,0.00003834629,0.00001877534,0.00003358879,0.00002091906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001407202,0.00001802509,0.0003948965,0.00003975197,0.000004297145,0.0000238126,0.00002432598,0.00004618831,0.9979008,0.00003172269,0.000048021,0.001327337],"study_design_scores_gemma":[0.000006388795,0.0003226135,0.005915873,0.000004793701,0.000007157526,0.0001465383,0.00002583194,0.0002540236,0.9919543,0.00003460634,0.001324239,0.00000360758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906165,0.002411605,0.003445545,0.0001063149,0.00005049296,0.00003863912,0.00123137,0.0000985966,0.002000907],"genre_scores_gemma":[0.9919512,0.0007067442,0.00225132,0.00008316335,0.00001210575,0.0000634212,0.001291517,0.00002617552,0.003614348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00322398,"threshold_uncertainty_score":0.01078528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02627318051818222,"score_gpt":0.3418850516547897,"score_spread":0.3156118711366075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}