{"id":"W4282922078","doi":"10.1158/1538-7445.am2022-4250","title":"Abstract 4250: Insights on genomic status and biomarker modulation using OncoPanel™ and BioMAP®platforms","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"","keywords":"Trastuzumab; Medicine; Tumor microenvironment; Antibody-dependent cell-mediated cytotoxicity; Cancer research; Breast cancer; Cancer; Immune system; Immunology; Monoclonal antibody; Oncology; Antibody; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001833612,0.0002908491,0.0001445628,0.000225731,0.00006634797,0.0003335483,0.0001636614,0.0002339285,0.00143516],"category_scores_gemma":[0.000171378,0.0001070891,0.0001519326,0.0001750902,0.0001436689,0.0002222932,0.0001500294,0.0003198689,0.0004363631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002444688,"about_ca_system_score_gemma":0.0001146645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004070945,"about_ca_topic_score_gemma":0.0003401956,"domain_scores_codex":[0.9998916,0.00001374799,0.00000445636,0.0000241718,0.00004864371,0.00001738353],"domain_scores_gemma":[0.9999527,0.00001199683,0.00001217949,0.00000361084,0.000009137912,0.00001032011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007362212,0.00004021288,0.0002263486,0.00003483535,0.000005044823,0.00003091018,0.00001207334,0.0004025238,0.9910693,0.0001304645,0.000155367,0.00781923],"study_design_scores_gemma":[0.00001067368,0.0004385671,0.004149861,0.00000653257,0.00001467215,0.0001423233,0.00002249954,0.004375807,0.9831222,0.0001446195,0.007560442,0.00001179134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9730377,0.00532975,0.01464187,0.0003509658,0.00008504622,0.00009535814,0.001013946,0.0002143278,0.005230954],"genre_scores_gemma":[0.9789409,0.00252651,0.01107105,0.000300724,0.00002862022,0.00007748106,0.000997037,0.00004090308,0.006016838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00143516,"threshold_uncertainty_score":0.004801095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1936220027343991,"score_gpt":0.4417882486844389,"score_spread":0.2481662459500397,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}