{"id":"W4282924487","doi":"10.1016/j.fertnstert.2022.05.030","title":"Molecular analysis suggests oligoclonality and metastasis of endometriosis lesions across anatomically defined subtypes","year":2022,"lang":"en","type":"article","venue":"Fertility and Sterility","topic":"Endometriosis Research and Treatment","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital; B.C. Women's Hospital & Health Centre; British Columbia Centre of Excellence for Women's Health; University of Calgary; Vancouver General Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; BC Cancer Foundation; Michael Smith Health Research BC; VGH and UBC Hospital Foundation; Calgary Laboratory Services","keywords":"Endometriosis; Medicine; Retrospective cohort study; Pathology; Germline mutation; Mutation; Oncology; Disease; Somatic cell; Internal medicine; Gene; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001456141,0.0001946274,0.0008463861,0.0003384303,0.0003243929,0.00002789406,0.0001093114,0.0000571386,0.0003001556],"category_scores_gemma":[0.002268452,0.0001650921,0.0003259354,0.001895807,0.0003341292,0.00006654164,0.0004720904,0.0002410772,8.379521e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001171451,"about_ca_system_score_gemma":0.00008590073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001150438,"about_ca_topic_score_gemma":0.0003135209,"domain_scores_codex":[0.9974222,0.0005200584,0.0004875635,0.0005612837,0.0006358637,0.0003730787],"domain_scores_gemma":[0.9976712,0.001140716,0.0001066114,0.000575783,0.0001516702,0.0003540399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02194449,0.001914318,0.9233573,0.0004213999,0.003631895,0.00009694802,0.000526615,0.00001337539,0.006627187,0.00006890208,0.00000978314,0.04138779],"study_design_scores_gemma":[0.001689976,0.0005476986,0.9853907,0.000005358272,0.0008013311,0.00001138634,0.0002303178,0.0001940446,0.01048937,0.0002340662,0.0002961423,0.0001095725],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944561,0.00323916,0.0001455037,0.0005008078,0.00001752033,0.0004749291,0.0009947557,0.00002850695,0.0001427343],"genre_scores_gemma":[0.9990337,0.0002017815,0.0004341858,0.00009622766,0.000003014287,0.00008176961,0.0001132559,0.000008509526,0.0000275923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06203344,"threshold_uncertainty_score":0.6732262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02951912716142334,"score_gpt":0.330852433825059,"score_spread":0.3013333066636356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}