{"id":"W4282926168","doi":"10.1007/s11064-022-03630-z","title":"EMMPRIN Promotes the Expression of MMP-9 and Exacerbates Neurological Dysfunction in a Mouse Model of Intracerebral Hemorrhage","year":2022,"lang":"en","type":"article","venue":"Neurochemical Research","topic":"Intracerebral and Subarachnoid Hemorrhage Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"National Natural Science Foundation of China","keywords":"Intracerebral hemorrhage; Medicine; Matrix metalloproteinase; Downregulation and upregulation; Microglia; Metalloproteinase; Monoclonal antibody; Basigin; Pathology; Antibody; Internal medicine; Immunology; Chemistry; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000431721,0.001142994,0.0007750139,0.001188168,0.0003476789,0.0004841633,0.0003959324,0.0008055238,0.001289882],"category_scores_gemma":[0.0002298437,0.0003889151,0.0006093389,0.0004401863,0.0006761879,0.0005856131,0.0004386111,0.00206551,0.000322701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004812516,"about_ca_system_score_gemma":0.0003277399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006511882,"about_ca_topic_score_gemma":0.001196414,"domain_scores_codex":[0.9995834,0.00005989808,0.00005353109,0.00005801005,0.000112036,0.0001331275],"domain_scores_gemma":[0.9996251,0.00002495361,0.0001515446,0.00003853986,0.00002822504,0.0001316277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001571875,0.0005104283,0.0005929202,0.0001109368,0.00003745224,0.0008641637,0.00004715872,0.000138772,0.9944373,0.0002177927,0.0001225352,0.001348563],"study_design_scores_gemma":[0.0001824004,0.003348335,0.02260261,0.00005366895,0.0001972612,0.001881704,0.0002628249,0.002154935,0.9667667,0.0002993865,0.002218005,0.00003217419],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953161,0.001038112,0.001987675,0.0002002123,0.0000852656,0.00005650894,0.0002995861,0.0001134466,0.0009030559],"genre_scores_gemma":[0.9911942,0.001774788,0.002417488,0.0001338321,0.00006240221,0.0001067401,0.0004893063,0.00002513431,0.003795956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001289882,"threshold_uncertainty_score":0.004315078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05909216178758269,"score_gpt":0.3238623153038436,"score_spread":0.2647701535162609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}