{"id":"W4282928153","doi":"10.1016/j.tice.2022.101850","title":"Role of Wnt/β-catenin pathway in cardiac lineage commitment of human umbilical cord mesenchymal stem cells by zebularine and 2'-deoxycytidine","year":2022,"lang":"en","type":"article","venue":"Tissue and Cell","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Wnt signaling pathway; Biology; Mesenchymal stem cell; Beta-catenin; Cell biology; LRP5; Cancer research; Downregulation and upregulation; Signal transduction; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002888153,0.0001518645,0.0005789384,0.00009341472,0.00005116077,0.000002542086,0.00005574134,0.00005253861,0.00009583143],"category_scores_gemma":[0.000003354328,0.0001304683,0.00003777332,0.0001437959,0.000104155,0.00001464631,0.00010821,0.0002436155,9.133561e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002671604,"about_ca_system_score_gemma":0.00002017176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002584279,"about_ca_topic_score_gemma":0.000005209654,"domain_scores_codex":[0.9989443,0.00007961238,0.0003421869,0.0002280436,0.0002311533,0.0001746662],"domain_scores_gemma":[0.9995704,0.00004608275,0.00008065396,0.0001555092,0.00002799533,0.0001193503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001043766,0.0002843518,0.003091589,0.0002162311,0.00003032949,0.00002774278,0.0008347451,0.00002756708,0.990747,0.000172458,0.0006466739,0.003816951],"study_design_scores_gemma":[0.001739289,0.002521791,0.002465745,0.00004655106,0.00005362869,0.00001508802,0.0009660186,0.0001612797,0.9685205,0.000006492292,0.02338302,0.0001206579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9739805,0.02509771,0.00001528914,0.0001181421,0.00008479677,0.0003426802,0.00005331746,0.00001577138,0.0002917525],"genre_scores_gemma":[0.9900198,0.0001966905,0.00008828644,0.0000105873,0.00007074127,0.00002524172,0.0000540727,0.00002037134,0.009514182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02490102,"threshold_uncertainty_score":0.5320342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00938233350440897,"score_gpt":0.2338169603784304,"score_spread":0.2244346268740214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}