{"id":"W4282932391","doi":"10.1158/1538-7445.am2022-273","title":"Abstract 273: Prostate cancer metastasis induces irregular bone formation associated to specific androgen dependent phenotypes","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Bone health and treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Bone mineral; Extracellular matrix; Prostate cancer; Pathology; Trabecula (gastropod); Androgen receptor; Matrix (chemical analysis); Stromal cell; Fibril; Chemistry; Medicine; Osteoporosis; Cancer; Biology; Cell biology; Biophysics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009315614,0.000213555,0.0001464758,0.0004265289,0.000249935,0.0002549471,0.0001339545,0.0001872124,0.004539142],"category_scores_gemma":[0.0001009427,0.0001668612,0.0001562172,0.000311846,0.0003084736,0.00006930254,0.0002037109,0.0003133642,0.0005336676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002380083,"about_ca_system_score_gemma":0.0002564821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002121087,"about_ca_topic_score_gemma":0.002506317,"domain_scores_codex":[0.9999064,0.000006697459,0.00000460541,0.00002010452,0.00004486975,0.0000173208],"domain_scores_gemma":[0.9999129,0.00001423142,0.00002255082,0.000011189,0.0000172058,0.00002206816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005846706,0.00001562015,0.002141159,0.0000436044,0.000005368,0.0003016642,0.00001343058,0.00008318345,0.9953924,0.00007014274,0.000139331,0.001735615],"study_design_scores_gemma":[0.00003709533,0.0006140278,0.2324122,0.00001508937,0.00003290931,0.01028539,0.0002044078,0.002391708,0.7466964,0.0001916048,0.007101411,0.00001776625],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9933409,0.0009693953,0.00270509,0.00009044944,0.00001951897,0.00002695673,0.0006284977,0.0001523543,0.002066868],"genre_scores_gemma":[0.9939042,0.0003491892,0.001143008,0.00005200426,0.000007071381,0.00002182955,0.0007158965,0.00003518495,0.003771695],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.004539142,"threshold_uncertainty_score":0.01518494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1218909687656413,"score_gpt":0.4195824741293929,"score_spread":0.2976915053637517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}