{"id":"W4282934381","doi":"10.1158/1538-7445.am2022-126","title":"Abstract 126: Defining how oxidative stress drives the evolution of aggressive breast cancers","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; Jewish General Hospital; McGill University","funders":"","keywords":"Breast cancer; Oxidative stress; Transcription factor; Cancer research; Metastasis; Malignancy; Medicine; Cancer; Disease; Biology; Bioinformatics; Immunology; Internal medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003617147,0.0002459358,0.0002864177,0.0004375133,0.0003383853,0.0009845406,0.0004174883,0.0006546882,0.002998795],"category_scores_gemma":[0.0004009416,0.0001700069,0.0002029094,0.0003047548,0.0006313722,0.0005930092,0.0005269974,0.0009247296,0.0006901109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001340967,"about_ca_system_score_gemma":0.0007282628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001819995,"about_ca_topic_score_gemma":0.002475836,"domain_scores_codex":[0.9997956,0.0000206644,0.00001469428,0.00006040085,0.00007741559,0.00003115815],"domain_scores_gemma":[0.9997559,0.00003323317,0.00007220011,0.00001906248,0.00005458606,0.00006494835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003543341,0.00006121967,0.005775878,0.0002658037,0.00001493119,0.000346755,0.0002142298,0.0002675797,0.9652615,0.003772477,0.003971703,0.01969367],"study_design_scores_gemma":[0.00008543955,0.0009754605,0.1307364,0.0002115482,0.00008658926,0.002744744,0.0007937118,0.004115059,0.6760108,0.005394821,0.17875,0.00009539009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9131603,0.02408521,0.01548842,0.00972858,0.001036899,0.0002196293,0.003077487,0.0005931204,0.03261042],"genre_scores_gemma":[0.9379661,0.01402942,0.01167093,0.00274413,0.000218784,0.0001742535,0.002746768,0.0001285144,0.0303211],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.002998795,"threshold_uncertainty_score":0.010032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02594127183512537,"score_gpt":0.3343711659341407,"score_spread":0.3084298940990153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}