{"id":"W4282935303","doi":"10.1093/stcltm/szac039","title":"The Tumorigenic Potential of Human Pluripotent Stem Cells","year":2022,"lang":"en","type":"article","venue":"Stem Cells Translational Medicine","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Azrieli Foundation; Rosetrees Trust","keywords":"Induced pluripotent stem cell; Teratoma; Biology; Cancer research; Regenerative medicine; Transplantation; Embryonic stem cell; Stem cell; Bioinformatics; Gene; Cell biology; Pathology; Medicine; Genetics; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001015007,0.0002266206,0.0002741711,0.0001016581,0.0006722109,0.00001162,0.0006326376,0.00007413603,0.0003097892],"category_scores_gemma":[0.000002218386,0.0001735267,0.0001889816,0.0002383178,0.000344439,0.000004855517,0.000160102,0.0002869551,0.00001238783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000361408,"about_ca_system_score_gemma":0.0001748635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003677396,"about_ca_topic_score_gemma":0.00001678546,"domain_scores_codex":[0.9968811,0.0003267843,0.0006476335,0.0004643611,0.001253036,0.0004270948],"domain_scores_gemma":[0.9988995,0.00007733956,0.0002126264,0.000502836,0.0001627667,0.0001449203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000208546,0.00008741125,0.0001033824,0.00005678687,0.0001129682,0.00001749773,0.000121704,0.002932498,0.9914347,0.0002849162,0.002566878,0.002072718],"study_design_scores_gemma":[0.002854426,0.001677654,0.0008369391,0.00003572046,0.0001009671,0.00005581833,0.001040012,0.0007083535,0.8947541,0.0002717487,0.09729879,0.0003655163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818878,0.008374758,0.001592387,0.002582732,0.00154025,0.001161822,0.0002359485,0.00002855993,0.002595763],"genre_scores_gemma":[0.9912795,0.0002630702,0.00003406945,0.00008469805,0.0003833003,0.00006982314,0.0001401999,0.00003870832,0.007706606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09668064,"threshold_uncertainty_score":0.7076214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01645382488690798,"score_gpt":0.2624997251497941,"score_spread":0.2460459002628861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}