{"id":"W4282935303","doi":"10.1093/stcltm/szac039","title":"The Tumorigenic Potential of Human Pluripotent Stem Cells","year":2022,"lang":"en","type":"article","venue":"Stem Cells Translational Medicine","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Azrieli Foundation; Rosetrees Trust","keywords":"Induced pluripotent stem cell; Teratoma; Biology; Cancer research; Regenerative medicine; Transplantation; Embryonic stem cell; Stem cell; Bioinformatics; Gene; Cell biology; Pathology; Medicine; Genetics; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005533255,0.0002024321,0.0001243842,0.0002362788,0.0001727112,0.0004690203,0.00009570815,0.0002224223,0.001389574],"category_scores_gemma":[0.0005005043,0.00006634709,0.000144093,0.0001880725,0.0002540035,0.0001889179,0.0003178492,0.0002757827,0.0003165987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001419213,"about_ca_system_score_gemma":0.0003658454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002420747,"about_ca_topic_score_gemma":0.0002746609,"domain_scores_codex":[0.9997535,0.00007563812,0.00002552087,0.0000363716,0.00008837656,0.00002056574],"domain_scores_gemma":[0.9997686,0.00009895815,0.00004101758,0.00003020711,0.00004248711,0.00001885401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001186164,0.00003940099,0.004852831,0.0003411483,0.0000233065,0.0005385151,0.0001501842,0.0006198593,0.9213102,0.005792692,0.0004752003,0.06573799],"study_design_scores_gemma":[0.00001144998,0.0011397,0.01304125,0.00013027,0.00008876647,0.002610243,0.0001523788,0.0009537527,0.9417333,0.002653895,0.03747152,0.00001349748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8486075,0.05399657,0.06701116,0.001943564,0.0001988605,0.0002398365,0.001723879,0.0002706799,0.02600788],"genre_scores_gemma":[0.9770414,0.01274098,0.0049065,0.0002133765,0.000050365,0.00005729499,0.0008638487,0.00001507605,0.004111069],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001389574,"threshold_uncertainty_score":0.004648566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01645382488690798,"score_gpt":0.2624997251497941,"score_spread":0.2460459002628861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}