{"id":"W4282936376","doi":"10.1158/1538-7445.am2022-2902","title":"Abstract 2902: Development of PSB202, a bifunctional antibody pair that target CD20 and CD37, for the treatment of B-cell malignancies","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cystic Fibrosis Canada","funders":"","keywords":"CD20; Antibody-dependent cell-mediated cytotoxicity; Obinutuzumab; Antibody; Monoclonal antibody; Radioimmunotherapy; Rituximab; Cancer research; B cell; Cell culture; Immunology; Non-Hodgkin's lymphoma; Lymphoma; Chemistry; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001281308,0.0004875903,0.00016972,0.0002301982,0.00008744694,0.0001759449,0.0002382373,0.0003168058,0.001972927],"category_scores_gemma":[0.00005944571,0.00009495935,0.0001863517,0.0001360688,0.00009435837,0.0001655292,0.0001602111,0.000377526,0.0008645082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002490824,"about_ca_system_score_gemma":0.0001895907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005853533,"about_ca_topic_score_gemma":0.0005791131,"domain_scores_codex":[0.9999408,0.00000805016,0.00000316492,0.00001440308,0.0000210341,0.00001257907],"domain_scores_gemma":[0.9999765,0.000001480057,0.000004236846,0.000001849254,0.000004969007,0.00001088023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009654841,0.00008274896,0.00008713775,0.00006085644,0.000008021341,0.00005858029,0.000007620745,0.0001225131,0.9908254,0.0001372959,0.0003231489,0.008190254],"study_design_scores_gemma":[0.0001212974,0.001061753,0.00139693,0.00001056008,0.0000314685,0.0006072317,0.000006096469,0.001185635,0.9812958,0.00004113754,0.01423605,0.000005997575],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9468581,0.01331497,0.02425105,0.0004068494,0.0002171741,0.00042417,0.001365031,0.0004721151,0.01269045],"genre_scores_gemma":[0.9761323,0.003710728,0.01029356,0.0001974769,0.00003952135,0.0001390943,0.001648716,0.00004673503,0.007791784],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.001972927,"threshold_uncertainty_score":0.006600082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1439242237165328,"score_gpt":0.4191626808209548,"score_spread":0.2752384571044221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}