{"id":"W4282939700","doi":"10.1097/01.hjh.0000835524.78117.27","title":"IMMUNE DYSREGULATION INDUCED BY SPIKE PROTEIN 1 OF SARS-COV-2 INCREASES ENDOTHELIAL CELL DYSFUNCTION VIA TYPE I AND TYPE III INTERFERON ACTIVATION PATHWAYS","year":2022,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Immune dysregulation; Medicine; Interferon; Immunology; Immune system; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001555808,0.0003650452,0.0002901459,0.0001849275,0.0001140801,0.0002486847,0.0001087763,0.0002744772,0.001647022],"category_scores_gemma":[0.000100225,0.0001159585,0.0003324946,0.0001342421,0.0002343487,0.0001647667,0.000174302,0.0005860829,0.0003249875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000201036,"about_ca_system_score_gemma":0.0001162573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001429669,"about_ca_topic_score_gemma":0.0002389373,"domain_scores_codex":[0.9998135,0.00003562164,0.00001342578,0.00003460974,0.00004818302,0.00005472352],"domain_scores_gemma":[0.9999213,0.000006838729,0.00002818455,0.000009559698,0.000009158425,0.00002492319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003550978,0.00005419225,0.0009069598,0.00003175497,0.000006975096,0.0001094906,0.00001365203,0.00002429658,0.9975927,0.00004589864,0.00005404877,0.0008047784],"study_design_scores_gemma":[0.0001277999,0.002424437,0.106935,0.00003535161,0.00008672448,0.00144475,0.0002242913,0.002208151,0.8830605,0.0002430718,0.003198756,0.00001122307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972705,0.0007585013,0.0007994648,0.000118942,0.00003566643,0.00001676326,0.0002345297,0.00003908195,0.0007265139],"genre_scores_gemma":[0.9973196,0.0006264746,0.0005837266,0.0001029692,0.00002123359,0.00003049587,0.0003166037,0.000007808362,0.0009909498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001647022,"threshold_uncertainty_score":0.005509853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02995116779854076,"score_gpt":0.2264283947485568,"score_spread":0.196477226950016,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}