{"id":"W4282943537","doi":"10.3390/mps5030050","title":"Application of Three-Dimensional Culture Method in the Cardiac Conduction System Research","year":2022,"lang":"en","type":"article","venue":"Methods and Protocols","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Heart and Stroke Foundation of Canada","keywords":"Cell culture; Cell biology; Embryonic stem cell; Cellular differentiation; Cell type; Biology; Cell; Stem cell; Induced pluripotent stem cell; Cell therapy; In vitro; Heart development; Directed differentiation; Myocyte; Computational biology; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01196093,0.0000720168,0.0001437252,0.00006652305,0.0002122168,0.00001532554,0.0002342661,0.00007068114,0.000006670432],"category_scores_gemma":[0.00007576335,0.00005111467,0.00004865807,0.0003015357,0.00006881476,0.000002737742,0.0002656448,0.0002959467,6.926319e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002647519,"about_ca_system_score_gemma":0.00006412381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001310453,"about_ca_topic_score_gemma":0.000006046359,"domain_scores_codex":[0.9945355,0.004402261,0.0001907342,0.0002973837,0.0003961598,0.0001779656],"domain_scores_gemma":[0.9993274,0.0001246904,0.00006172536,0.0003405807,0.0001173078,0.00002830459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001597789,0.00005253637,0.001272229,0.0001541001,0.00001769384,9.925806e-7,0.000126676,0.0001598269,0.9673752,0.001199921,0.000597655,0.02888343],"study_design_scores_gemma":[0.0009251879,0.001229329,0.003876711,0.00004015127,0.00001270145,0.00006446474,0.001598915,0.005061266,0.5140034,0.001599215,0.4713745,0.000214152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"protocol","genre_scores_codex":[0.158806,0.004469607,0.4592016,0.001619379,0.0002849043,0.3684087,0.0002839066,0.00004793162,0.00687792],"genre_scores_gemma":[0.2023233,0.00001623987,0.2717803,0.00009125704,0.0002967371,0.5246115,0.0001520107,0.00004116457,0.000687503],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.4707769,"threshold_uncertainty_score":0.4145443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08612298700682045,"score_gpt":0.4784422143638911,"score_spread":0.3923192273570706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}