{"id":"W4282943600","doi":"10.1111/cts.13350","title":"A randomized, placebo‐controlled study to evaluate safety and pharmacokinetics of inhaled ribavirin","year":2022,"lang":"en","type":"article","venue":"Clinical and Translational Science","topic":"Respiratory viral infections research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Bausch Health (Canada)","funders":"","keywords":"Pharmacokinetics; Ribavirin; Medicine; Placebo; Randomized controlled trial; Coronavirus disease 2019 (COVID-19); Pharmacology; 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); MEDLINE; Intensive care medicine; Internal medicine; Virology; Alternative medicine; Chemistry; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003673792,0.001499206,0.003875594,0.0004584597,0.0007779633,0.0009798948,0.001115769,0.002519856,0.009544445],"category_scores_gemma":[0.003923632,0.001108929,0.001475854,0.0004016363,0.002014916,0.001040641,0.0004674485,0.002640586,0.001163212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006347725,"about_ca_system_score_gemma":0.001759141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005968829,"about_ca_topic_score_gemma":0.0008940464,"domain_scores_codex":[0.9978126,0.001221174,0.0001613011,0.0003973002,0.0001845064,0.0002230579],"domain_scores_gemma":[0.9971365,0.001033904,0.0005595468,0.0003190994,0.0002792101,0.0006717585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9816378,0.009938333,0.0005747731,0.0002549126,0.0004541324,0.00003236603,0.00002706998,0.00006248278,0.002600745,0.00005559529,0.0002321783,0.00412964],"study_design_scores_gemma":[0.9039925,0.09378186,0.001264092,0.0000158906,0.0002478946,0.0000171622,0.00001162801,0.0001382128,0.000193507,0.00006814607,0.0002610293,0.000007998497],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811297,0.003001197,0.001190558,0.0006299081,0.001124588,0.01064535,0.0007540527,0.0001149713,0.001409678],"genre_scores_gemma":[0.9787154,0.001265778,0.002787658,0.001338462,0.0009144331,0.01186889,0.0006039793,0.00001846408,0.002486837],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009544445,"threshold_uncertainty_score":0.03192931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1096851904435797,"score_gpt":0.482317054010773,"score_spread":0.3726318635671932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}