{"id":"W4282946122","doi":"10.1158/1538-7445.am2022-6317","title":"Abstract 6317: Molecular subtyping in prostate cancer associate with outcomes to abiraterone and ipatasertib treatment from the phase III IPATential150 trial","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Prostate cancer; Cell cycle; Cancer research; Cancer; Transcriptome; Internal medicine; Prostate; Oncology; Medicine; Biology; Gene; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008115724,0.0002829606,0.0005886629,0.0001859899,0.0002044822,0.0005258324,0.0002029233,0.0001851094,0.002505552],"category_scores_gemma":[0.001042692,0.0001093625,0.0008605435,0.0003786722,0.0001629808,0.0001636097,0.000301413,0.0006401986,0.0002920993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002399434,"about_ca_system_score_gemma":0.0004111732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009267211,"about_ca_topic_score_gemma":0.002309423,"domain_scores_codex":[0.9995893,0.0001260827,0.0000297905,0.0001067425,0.000107009,0.00004106584],"domain_scores_gemma":[0.9995446,0.0001183703,0.0001388835,0.0000442586,0.00005906695,0.00009472905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.1094629,0.0007754331,0.6142504,0.001161516,0.006477631,0.0001729691,0.0001941202,0.00513714,0.06686182,0.0004490087,0.01817979,0.1768773],"study_design_scores_gemma":[0.004085278,0.004721743,0.9699848,0.00009319875,0.003065404,0.0003292896,0.0001261299,0.004661847,0.005039406,0.000977267,0.006880413,0.00003519396],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9886081,0.002186096,0.0009773624,0.0002814945,0.00005617779,0.00008332133,0.005707563,0.00005305078,0.002046847],"genre_scores_gemma":[0.9890131,0.0003429749,0.0004655004,0.0002674979,0.00004287021,0.00009674338,0.008988183,0.00002174049,0.0007614359],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.002505552,"threshold_uncertainty_score":0.008381844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.104751469679435,"score_gpt":0.4480990768835661,"score_spread":0.3433476072041311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}