{"id":"W4282961803","doi":"10.1158/1538-7445.am2022-5734","title":"Abstract 5734: The effect of PRAME on retinoid response and cell proliferation in cutaneous and head and neck squamous cell carcinoma","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Cancer research; Head and neck squamous-cell carcinoma; Retinoid; Cell growth; Cell culture; Biology; Cell; Cell cycle; Cancer; Medicine; Internal medicine; Retinoic acid; Head and neck cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001377182,0.0002154053,0.0004118365,0.0003816361,0.0002549539,0.0002564178,0.000223893,0.0003335798,0.005754804],"category_scores_gemma":[0.000125987,0.0001357709,0.0004558307,0.0002877498,0.0001895572,0.0001971267,0.0001679182,0.0007052819,0.001037603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001989176,"about_ca_system_score_gemma":0.0002962179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001228971,"about_ca_topic_score_gemma":0.001686751,"domain_scores_codex":[0.9998312,0.00002406768,0.00001959345,0.0000356631,0.0000511461,0.00003836077],"domain_scores_gemma":[0.9999206,0.00001694103,0.000009926769,0.00001396545,0.00001973528,0.00001884602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003876442,0.0001223637,0.0004453922,0.0000833185,0.00001179274,0.00006486957,0.00001724184,0.00005073388,0.9952899,0.00004598748,0.0002318737,0.003248839],"study_design_scores_gemma":[0.00005987761,0.001349912,0.01658669,0.00001336068,0.00004762086,0.0002928859,0.00007348261,0.0006079806,0.9758402,0.00003145014,0.005088388,0.000008168574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878076,0.005177861,0.001090106,0.0002067071,0.0001286109,0.00008995049,0.001404511,0.00009829864,0.00399634],"genre_scores_gemma":[0.9841644,0.002049541,0.001550262,0.0001193887,0.00002713052,0.00009890324,0.001887636,0.00002136213,0.01008145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005754804,"threshold_uncertainty_score":0.0192517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02076201019566685,"score_gpt":0.3204493167109208,"score_spread":0.2996873065152539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}