{"id":"W4282963616","doi":"10.1139/cjpp-2022-0126","title":"Endothelin system expression in the kidney following cisplatin-induced acute kidney injury in male and female mice","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Chemotherapy-induced organ toxicity mitigation","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Cisplatin; Acute kidney injury; Kidney; Endothelin receptor; Medicine; Endocrinology; Internal medicine; Renal medulla; Endothelin 1; Receptor; Pharmacology; Biology; Chemotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006149091,0.0001254564,0.0003480548,0.0003599744,0.0001854562,0.000006792807,0.0001415232,0.0001049676,0.0004731445],"category_scores_gemma":[0.00005607818,0.0001051326,0.00005584526,0.0002038036,0.00007054285,0.00007764611,0.00002601183,0.0007689277,0.00000129824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002049272,"about_ca_system_score_gemma":0.0008645737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004093682,"about_ca_topic_score_gemma":0.0001154213,"domain_scores_codex":[0.9986026,0.0005136291,0.0003433287,0.0001752705,0.00008827308,0.0002769571],"domain_scores_gemma":[0.9992222,0.00009169315,0.0001752887,0.00008157318,0.00002614471,0.0004031235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002714574,0.00002992925,0.007198026,0.00006978676,0.0000501269,0.0006302668,0.002801526,0.000003713538,0.986719,0.00001674061,0.002033041,0.0001763851],"study_design_scores_gemma":[0.006690328,0.0008728761,0.01749059,0.0001778565,0.0001888348,0.003187712,0.002254611,0.0001944279,0.965858,0.0001539147,0.002729813,0.0002010189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948705,0.0001762992,0.000001820769,0.003930368,0.0005831213,0.0002707246,0.00004923642,0.000003297333,0.0001146112],"genre_scores_gemma":[0.9915577,0.00003072522,0.00006572844,0.008073956,0.000187148,0.00001750768,0.00001279324,0.00001406339,0.00004033609],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02086098,"threshold_uncertainty_score":0.5180601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01436962239241222,"score_gpt":0.2822795129607621,"score_spread":0.2679098905683499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}