{"id":"W4282971285","doi":"10.1158/1538-7445.am2022-1229","title":"Abstract 1229: miRNA and response to trastuzumab","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kelowna General Hospital","funders":"","keywords":"Trastuzumab; Lapatinib; Medicine; Pertuzumab; Oncology; Internal medicine; Clinical endpoint; Breast cancer; Cancer; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009361776,0.0002739483,0.0006246075,0.0004388269,0.00012054,0.0007263324,0.0001727057,0.0004380961,0.002357797],"category_scores_gemma":[0.002596947,0.0001233506,0.0003471392,0.0005251489,0.0001488134,0.0002311804,0.000231802,0.0005778022,0.0008709308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003123829,"about_ca_system_score_gemma":0.0001836255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002536768,"about_ca_topic_score_gemma":0.000191698,"domain_scores_codex":[0.999339,0.0002017032,0.00007676224,0.0001234214,0.0002191229,0.00003996976],"domain_scores_gemma":[0.999051,0.0003460111,0.0002866023,0.00005287955,0.0001692817,0.00009424373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0251933,0.0007864722,0.7419161,0.0004503792,0.001105614,0.0007151404,0.0001201386,0.002828972,0.1041917,0.0002846445,0.004198026,0.1182095],"study_design_scores_gemma":[0.0004112892,0.004045505,0.9470936,0.00005224663,0.0005884213,0.002005929,0.00007208255,0.008932095,0.02745587,0.0008189929,0.00848509,0.00003893839],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853064,0.006555079,0.001801956,0.0004826698,0.0001379968,0.00006979155,0.002142125,0.00007771359,0.003426284],"genre_scores_gemma":[0.9965417,0.000427613,0.0006036576,0.0001438108,0.00008456247,0.00003580969,0.0009734521,0.00001487115,0.001174482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002357797,"threshold_uncertainty_score":0.007887661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06302451686101232,"score_gpt":0.4115005039291933,"score_spread":0.3484759870681809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}