{"id":"W4282973401","doi":"10.3389/fnmol.2022.927334","title":"Iron Neurotoxicity and Protection by Deferoxamine in Intracerebral Hemorrhage","year":2022,"lang":"en","type":"review","venue":"Frontiers in Molecular Neuroscience","topic":"Intracerebral and Subarachnoid Hemorrhage Research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"National Key Research and Development Program of China; China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Deferoxamine; Intracerebral hemorrhage; Medicine; Neurotoxicity; Stroke (engine); Brain edema; Hematoma; Anesthesia; Pharmacology; Toxicity; Internal medicine; Surgery; Glasgow Coma Scale","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002634465,0.0004888666,0.0007251536,0.001338703,0.0001791767,0.0004933498,0.0004180504,0.000597139,0.002033354],"category_scores_gemma":[0.0003156535,0.0001351654,0.0002817132,0.0009279608,0.0002030644,0.0005144647,0.000350646,0.000769529,0.0008499183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002708319,"about_ca_system_score_gemma":0.0005628928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000745906,"about_ca_topic_score_gemma":0.001462114,"domain_scores_codex":[0.9999449,0.00001018723,0.00001012594,0.000009336572,0.00001871153,0.000006671968],"domain_scores_gemma":[0.999923,0.00003197152,0.00001249902,0.000001726741,0.00002154847,0.000009182797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000170377,0.00009541783,0.0002204201,0.02709133,0.00009492192,0.0003426233,0.00009753605,0.0002709397,0.004014148,0.003020709,0.02075934,0.9438223],"study_design_scores_gemma":[0.00004956824,0.0003186809,0.001758215,0.006426962,0.0002288758,0.002453909,0.00008863334,0.0001210259,0.001459529,0.002152271,0.9849198,0.00002255663],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000225756,0.998909,0.00005268912,0.0001004969,0.00007839875,0.000002853428,0.00001366231,0.000003705607,0.0006134217],"genre_scores_gemma":[0.001142818,0.998312,0.00006768315,0.00008828035,0.00007893291,0.000004074839,0.00002318948,5.220431e-7,0.0002825693],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002033354,"threshold_uncertainty_score":0.006802261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03280331316256736,"score_gpt":0.3010243780197507,"score_spread":0.2682210648571833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}