{"id":"W4282975662","doi":"10.1158/1538-7445.am2022-1431","title":"Abstract 1431: ADO contributes to tumour initiating phenotypes","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Biology; Gene knockdown; Cancer research; Cell growth; Cell culture; Clonogenic assay; Cell biology; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001390664,0.0006064901,0.0004370431,0.0006354229,0.0003138958,0.0007162976,0.0003209591,0.0008280066,0.01205898],"category_scores_gemma":[0.0002113303,0.0002503984,0.0004702122,0.0003576231,0.0004052111,0.0001952861,0.0004622033,0.001472653,0.004318096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002706043,"about_ca_system_score_gemma":0.0002538946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004234677,"about_ca_topic_score_gemma":0.0003788222,"domain_scores_codex":[0.9997631,0.00002123529,0.00002969407,0.00006414606,0.00007485187,0.00004705408],"domain_scores_gemma":[0.9995468,0.00004753285,0.0001280607,0.00004540861,0.00003757269,0.0001946365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001989517,0.00006242144,0.0007229375,0.0001202707,0.00001511954,0.0007445455,0.00002019258,0.00007248946,0.9951566,0.0003641412,0.0004879234,0.002034494],"study_design_scores_gemma":[0.0001171349,0.0005262634,0.04549894,0.00007551814,0.0001289235,0.01090721,0.0001785445,0.002816967,0.8887459,0.0008326272,0.05012894,0.00004301113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9603897,0.003821693,0.009305255,0.0008553183,0.0004969169,0.0001278391,0.01027429,0.001218121,0.01351104],"genre_scores_gemma":[0.9726216,0.001394419,0.00163399,0.0002189051,0.00005423147,0.00008168654,0.005542316,0.0003869213,0.01806588],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01205898,"threshold_uncertainty_score":0.04034126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05122138103506957,"score_gpt":0.3776997483880625,"score_spread":0.326478367352993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}