{"id":"W4282980100","doi":"10.1245/s10434-022-12013-1","title":"ASO Author Reflections: Sentinel Lymph Node Biopsy in BRCA1/2 Germline Pathogenic Variant Carriers Undergoing Risk-Reducing Mastectomy","year":2022,"lang":"en","type":"letter","venue":"Annals of Surgical Oncology","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Fonds de Recherche du Québec - Santé","keywords":"Surgical oncology; Medicine; Mastectomy; Sentinel lymph node; Germline; Biopsy; Oncology; Breast cancer; General surgery; Internal medicine; Cancer; Gene; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00133873,0.0005547944,0.0008208691,0.0008730266,0.002567818,0.002309958,0.001464942,0.02954339,0.005913313],"category_scores_gemma":[0.0144428,0.0006704502,0.0008211609,0.0006031138,0.001131933,0.00145429,0.0007462419,0.0226365,0.003407846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002667811,"about_ca_system_score_gemma":0.003038642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006810667,"about_ca_topic_score_gemma":0.01220113,"domain_scores_codex":[0.9989552,0.0002201554,0.0001275416,0.0001568632,0.0002814284,0.0002587768],"domain_scores_gemma":[0.9956229,0.001992388,0.0002750044,0.0001429268,0.0008791398,0.001087677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001216436,0.0001034762,0.005603968,0.00005440006,0.00002468401,0.02025508,0.0001803971,0.0001733137,0.0005175601,0.001150344,0.9613092,0.01050597],"study_design_scores_gemma":[0.0003970251,0.0004626906,0.01623922,0.0008679468,0.0001757498,0.04785313,0.002105541,0.00294499,0.001438606,0.01191058,0.9153919,0.0002127286],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002313804,0.0008881754,0.0001416846,0.9521272,0.03974989,0.00002293173,0.00009160113,0.00003454735,0.004630302],"genre_scores_gemma":[0.02271832,0.001875617,0.0004777924,0.8901287,0.07359064,0.00005405868,0.00008756767,0.00003944342,0.01102791],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02954339,"threshold_uncertainty_score":0.01978201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04992387376556623,"score_gpt":0.3596905403931423,"score_spread":0.3097666666275761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}