{"id":"W4282982088","doi":"10.3390/life12060896","title":"Anti-Inflammatory, Antioxidant, and Anti-Atherosclerotic Effects of Natural Supplements on Patients with FMF-Related AA Amyloidosis: A Non-Randomized 24-Week Open-Label Interventional Study","year":2022,"lang":"en","type":"article","venue":"Life","topic":"Pancreatitis Pathology and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Internal medicine; Gastroenterology; Malondialdehyde; Amyloidosis; Asymmetric dimethylarginine; Oxidative stress; C-reactive protein; Renal function; Serum amyloid A; Endothelial dysfunction; Familial Mediterranean fever; Serum Amyloid A Protein; Proteinuria; Inflammation; Endocrinology; Kidney; Arginine; Biochemistry; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004030202,0.0002710845,0.001012875,0.0001759201,0.0002330682,0.00001967977,0.0001649812,0.00004997731,0.0001349131],"category_scores_gemma":[0.0001276896,0.0002014634,0.00009273523,0.0001944074,0.0001844354,0.0001047473,0.0002503442,0.0002938432,0.00001100141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005916315,"about_ca_system_score_gemma":0.00007315991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006820702,"about_ca_topic_score_gemma":0.000007595507,"domain_scores_codex":[0.9978299,0.0004857653,0.0005275848,0.0004356864,0.0004606233,0.0002604141],"domain_scores_gemma":[0.9989529,0.0002239856,0.0003259246,0.000298518,0.0000768664,0.0001217513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01855367,0.01907232,0.9569771,0.0001850225,0.002290714,0.0002751668,0.001108171,0.000006066701,0.001085364,0.0001077361,0.0001918999,0.0001467189],"study_design_scores_gemma":[0.3063804,0.006569694,0.6851621,0.0003231372,0.0007166108,0.00001503479,0.0001689223,0.00005762908,0.000436533,0.00001832215,0.000008366304,0.000143294],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944958,0.0003028301,0.000009711927,0.00007391987,0.0003822409,0.004522935,0.00007228168,0.00003231042,0.0001079616],"genre_scores_gemma":[0.9986402,0.00002309723,0.0001388087,0.0001565721,0.00001476344,0.0005659019,0.0001602097,0.00003286287,0.0002675245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2878267,"threshold_uncertainty_score":0.8215438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01202581012245238,"score_gpt":0.2653360662383499,"score_spread":0.2533102561158975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}