{"id":"W4282984391","doi":"10.1158/1538-7445.am2022-5914","title":"Abstract 5914: E-cadherin and beta-catenin in oral dysplasia progression","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; Dalhousie University; University of British Columbia","funders":"","keywords":"Adherens junction; Epithelial–mesenchymal transition; Cadherin; Beta-catenin; Epithelial dysplasia; Immunohistochemistry; Catenin; Wnt signaling pathway; Cancer; Pathology; Tumor progression; Medicine; Biopsy; Cancer research; Biology; Cell; Internal medicine; Signal transduction; Metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003431035,0.0002572043,0.0002935262,0.001308815,0.0002837951,0.0004089629,0.0002026292,0.0003194998,0.004292763],"category_scores_gemma":[0.0005871189,0.0001406992,0.000197893,0.0006276832,0.0002086723,0.0002438215,0.0002769568,0.0002228375,0.0004836789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001879223,"about_ca_system_score_gemma":0.0001807046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008981918,"about_ca_topic_score_gemma":0.0008841146,"domain_scores_codex":[0.9998567,0.00003072978,0.00002206822,0.00003210255,0.00003836995,0.000019954],"domain_scores_gemma":[0.999747,0.00005534706,0.00008095401,0.0000174997,0.00005601652,0.00004318589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002842962,0.0002882471,0.9208628,0.000218642,0.0001050862,0.001538907,0.0001881683,0.0001156651,0.05068068,0.0001038068,0.0004520264,0.02260299],"study_design_scores_gemma":[0.00004867696,0.0005618169,0.9902989,0.00002117929,0.00007222627,0.003219266,0.000105621,0.0003377984,0.004214278,0.00008241997,0.001032734,0.000005065923],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973182,0.001449142,0.000129411,0.00002569368,0.000006007431,0.00002505951,0.0001990984,0.000006328626,0.0008410771],"genre_scores_gemma":[0.998376,0.0003193441,0.0001805389,0.00001013664,0.00001176567,0.00001622539,0.000263688,0.000001863698,0.0008203828],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004292763,"threshold_uncertainty_score":0.01436073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04805044696909787,"score_gpt":0.4015696963847803,"score_spread":0.3535192494156824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}