{"id":"W4283010889","doi":"10.1101/2022.06.16.496489","title":"Calcineurin associates with centrosomes and regulates cilia length maintenance","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Government of Ontario; National Institutes of Health; Canadian Institutes of Health Research; Genome Canada; Ontario Genomics; Rheinische Friedrich-Wilhelms-Universität Bonn","keywords":"Calcineurin; Cell biology; Cilium; Biology; Centrosome; Centriole; Phosphatase; Ciliogenesis; Mitosis; Cell cycle; Biochemistry; Cell; Transplantation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000124004,0.0002142807,0.0001473599,0.0003920307,0.0002942104,0.0003994282,0.0001987349,0.00023537,0.001032586],"category_scores_gemma":[0.000146809,0.0001156648,0.0002082088,0.000166038,0.0002161385,0.0001819891,0.0002050593,0.0002357887,0.000233093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008352777,"about_ca_system_score_gemma":0.0003014084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002790791,"about_ca_topic_score_gemma":0.003873016,"domain_scores_codex":[0.9998755,0.000008978561,0.000008802381,0.00002826633,0.00005585754,0.00002248187],"domain_scores_gemma":[0.9998602,0.00001302573,0.00004253828,0.00001218227,0.00002381335,0.00004818551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000337668,0.000005457684,0.001023347,0.00002931361,0.000004799547,0.00007451198,0.0000101366,0.00003949421,0.9977294,0.00009299556,0.00004358834,0.0009132755],"study_design_scores_gemma":[0.00001774702,0.00009698368,0.1042101,0.00002011131,0.00002704812,0.0006960591,0.00006196003,0.003110205,0.8870516,0.0001487018,0.004551961,0.000007440859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898548,0.00496374,0.002304013,0.0001175929,0.00002740451,0.0000143932,0.0002065503,0.00009833868,0.002413153],"genre_scores_gemma":[0.9955584,0.0007502887,0.0008992137,0.00003206163,0.00001110214,0.000008640931,0.0002157223,0.00001571514,0.002508902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002790791,"threshold_uncertainty_score":0.006060421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005305028670022358,"score_gpt":0.1942788398727308,"score_spread":0.1889738112027084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}