{"id":"W4283068621","doi":"10.3390/polym14122447","title":"Hepatotropic Peptides Grafted onto Maleimide-Decorated Nanoparticles: Preparation, Characterization and In Vitro Uptake by Human HepaRG Hepatoma Cells","year":2022,"lang":"en","type":"article","venue":"Polymers","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Circulatory and Respiratory Health; Cancéropôle Grand Ouest; Centre National de la Recherche Scientifique; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Labex Iron","keywords":"Maleimide; In vitro; Characterization (materials science); Peptide; Chemistry; Nanoparticle; Polymer chemistry; Materials science; Biochemistry; Nanotechnology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001383942,0.0002482048,0.0001727632,0.00008332812,0.00007792637,0.0001357782,0.0001087543,0.000153786,0.0003640168],"category_scores_gemma":[0.00006281236,0.0001137803,0.0001401232,0.000107009,0.0001003666,0.00009517719,0.00009364734,0.000196961,0.0002399153],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001743457,"about_ca_system_score_gemma":0.00009163178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001363407,"about_ca_topic_score_gemma":0.001636513,"domain_scores_codex":[0.999933,0.00001132357,0.000005560962,0.0000170287,0.00002017604,0.00001285479],"domain_scores_gemma":[0.9999628,0.00000845008,0.000007731561,0.00000535502,0.000008763446,0.000006863816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002027742,0.000005792097,0.00007532884,0.00001599367,0.000001643064,0.00002732432,0.00001282866,0.00003652008,0.9993414,0.00001507655,0.000007273847,0.0004405563],"study_design_scores_gemma":[0.000003642315,0.00005713841,0.001429289,0.000001561734,0.000005036452,0.00006999029,0.000008628601,0.0005441591,0.9973837,0.000008598266,0.0004861091,0.00000220659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918056,0.0009675791,0.005682081,0.00003434256,0.00001406194,0.00003959875,0.0002080787,0.00005014447,0.001198697],"genre_scores_gemma":[0.9881253,0.0009452123,0.007272035,0.00003468986,0.000007005322,0.00004291678,0.0003686712,0.00002739354,0.003176822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001363407,"threshold_uncertainty_score":0.002710938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007381450501664744,"score_gpt":0.2295442924558591,"score_spread":0.2221628419541943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}