{"id":"W4283071318","doi":"10.3390/molecules27123869","title":"TNKPVI, a Putative Bioaccessible Pharmacophore of Anti-Inflammatory Potato Patatin-Derived Decapeptide DIKTNKPVIF","year":2022,"lang":"en","type":"article","venue":"Molecules","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; State University of New York Fredonia; University of Ottawa","keywords":"Chemistry; Peptide; Trypsin; Chymotrypsin; Biochemistry; Proteases; Pharmacophore; Cathepsin G; Pepsin; Lipopolysaccharide; Hydrolysate; Pharmacology; Enzyme; Hydrolysis; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005583874,0.0002320543,0.0001895236,0.00009888514,0.00005787314,0.0001591243,0.0001396168,0.0002656879,0.0008882848],"category_scores_gemma":[0.0001013902,0.00007014589,0.0001587938,0.0001115163,0.00009756913,0.0001530274,0.0001295923,0.0003131324,0.0003114996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001352613,"about_ca_system_score_gemma":0.0000959883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002310766,"about_ca_topic_score_gemma":0.0002262268,"domain_scores_codex":[0.9999565,0.000007297771,0.000003070986,0.00001283491,0.00001022016,0.000009991255],"domain_scores_gemma":[0.9999751,0.000003543576,0.000008526375,0.000001825893,0.000003971797,0.000007036248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002148411,0.00001920252,0.0001381393,0.0001085257,0.000007209267,0.00009622381,0.000007742067,0.0003814523,0.9958269,0.00006419376,0.00005646778,0.003078981],"study_design_scores_gemma":[0.0000563059,0.0008511372,0.003392402,0.0000173983,0.00002762727,0.0008767925,0.00002852905,0.002508937,0.9868189,0.00007763399,0.005332723,0.00001152947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833577,0.003469306,0.009651451,0.0001019187,0.00003724965,0.00007591272,0.0006148195,0.00005438717,0.002637167],"genre_scores_gemma":[0.9887347,0.001642794,0.006415746,0.0001138706,0.000008445886,0.00004327968,0.0009446964,0.00001567046,0.002080787],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008882848,"threshold_uncertainty_score":0.002971649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009009329571438643,"score_gpt":0.2525146405166188,"score_spread":0.2435053109451802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}