{"id":"W4283079234","doi":"10.3390/pathogens11060693","title":"Probe Capture Enrichment Methods for HIV and HCV Genome Sequencing and Drug Resistance Genotyping","year":2022,"lang":"en","type":"review","venue":"Pathogens","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"","keywords":"Sanger sequencing; Genotyping; Biology; Massive parallel sequencing; DNA sequencing; Genome; Computational biology; Whole genome sequencing; Virology; Deep sequencing; Genetics; DNA; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001240752,0.0008680873,0.0007272852,0.00160419,0.000650064,0.0007604459,0.0009043485,0.001380282,0.004853828],"category_scores_gemma":[0.001923739,0.000634536,0.0006523955,0.001200242,0.0004094958,0.000688952,0.001140763,0.00148966,0.004631184],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006018582,"about_ca_system_score_gemma":0.0006620276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001479095,"about_ca_topic_score_gemma":0.002884831,"domain_scores_codex":[0.9982595,0.0003874605,0.00006636802,0.0004215855,0.0007418416,0.0001232682],"domain_scores_gemma":[0.9993882,0.0002472384,0.00007221245,0.00007152597,0.0001776891,0.00004317686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002331165,0.0001096984,0.001383379,0.0007855501,0.00007466893,0.0002840623,0.000191797,0.00153701,0.827776,0.002891177,0.006068597,0.158665],"study_design_scores_gemma":[0.00005121946,0.0005033368,0.00783139,0.0003031686,0.0001464912,0.001552178,0.0001604211,0.02803856,0.8117328,0.003508303,0.1460122,0.0001599196],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.04504185,0.01842196,0.9126506,0.001025285,0.0004465812,0.001075743,0.002726085,0.005330776,0.01328108],"genre_scores_gemma":[0.1751471,0.01510777,0.776385,0.002173845,0.0001721001,0.002554162,0.00617149,0.0008859304,0.02140258],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.004853828,"threshold_uncertainty_score":0.01623762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05571146625448847,"score_gpt":0.3533919128151366,"score_spread":0.2976804465606481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}