{"id":"W4283166986","doi":"10.3389/fimmu.2022.900553","title":"Gasdermins in Innate Host Defense Against Entamoeba histolytica and Other Protozoan Parasites","year":2022,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Entamoeba histolytica; Innate immune system; Host (biology); Protozoan parasite; Entamoeba; Biology; Protozoan infection; Microbiology; Immunology; Parasite hosting; Ecology; Immune system; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002289758,0.0005322861,0.0005555173,0.001257027,0.0002426968,0.0007410425,0.0003668572,0.0007435707,0.001194728],"category_scores_gemma":[0.0002045346,0.0001816204,0.00041068,0.0008229265,0.000269465,0.001043995,0.0004508213,0.0008315576,0.0005940062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005367855,"about_ca_system_score_gemma":0.0005369505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006524595,"about_ca_topic_score_gemma":0.0007830193,"domain_scores_codex":[0.9998631,0.0000179839,0.0000237052,0.00003084055,0.00003740333,0.00002685401],"domain_scores_gemma":[0.9999088,0.00002063932,0.00003272706,0.00000237183,0.00002147763,0.00001395621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007521716,0.0001558576,0.004429302,0.02869113,0.0002733401,0.003662328,0.0006712183,0.001109973,0.2026054,0.01033406,0.02220917,0.725106],"study_design_scores_gemma":[0.00002960689,0.0005129278,0.01204849,0.001726271,0.0003386895,0.01027079,0.0003692578,0.0003615655,0.03865007,0.003081908,0.9325401,0.00007043598],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003875152,0.9937737,0.0003993762,0.0002132517,0.0001311119,0.000008873393,0.00007419258,0.00002217594,0.00150215],"genre_scores_gemma":[0.02547572,0.9698635,0.0008664274,0.0004576155,0.0003959207,0.00001899535,0.0003182165,0.000007062748,0.002596692],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001257027,"threshold_uncertainty_score":0.00399673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0265848447407036,"score_gpt":0.3048807120969886,"score_spread":0.278295867356285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}