{"id":"W4283166986","doi":"10.3389/fimmu.2022.900553","title":"Gasdermins in Innate Host Defense Against Entamoeba histolytica and Other Protozoan Parasites","year":2022,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Entamoeba histolytica; Innate immune system; Host (biology); Protozoan parasite; Entamoeba; Biology; Protozoan infection; Microbiology; Immunology; Parasite hosting; Ecology; Immune system; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001981297,0.000419578,0.001776338,0.001110172,0.00009440107,0.00001053523,0.0001317132,0.0003955323,0.0002243009],"category_scores_gemma":[0.0001108406,0.0003644695,0.0001994123,0.0005170602,0.0002859989,0.00004090564,0.0001376515,0.0009059493,0.00002771639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001090381,"about_ca_system_score_gemma":0.0003304968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001812296,"about_ca_topic_score_gemma":0.00005140711,"domain_scores_codex":[0.9979886,0.0002927712,0.0006235033,0.0005295028,0.0001089226,0.0004566982],"domain_scores_gemma":[0.9991536,0.00008685687,0.000233219,0.0004573214,0.00001400593,0.00005502456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001265057,0.0007024028,0.05075996,0.00233666,0.0008847964,0.001122999,0.0003763744,1.731662e-7,0.000001038471,0.0001586493,0.001326604,0.9422038],"study_design_scores_gemma":[0.00152971,0.0002818209,0.0009616678,0.001761322,0.0003579756,0.0004884324,0.0001494415,0.000005018958,6.428389e-7,0.00005214583,0.9941471,0.0002647644],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009547168,0.9888795,0.00001803095,0.00003317215,0.0008685207,0.00261064,0.00004274588,0.00004114506,0.006551532],"genre_scores_gemma":[0.0001849298,0.9955767,0.0007145595,0.0001467008,0.00003346568,0.001714603,0.000145168,0.00007835655,0.001405559],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9928204,"threshold_uncertainty_score":0.9998807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0265848447407036,"score_gpt":0.3048807120969886,"score_spread":0.278295867356285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}