{"id":"W4283206789","doi":"10.1177/02698811221104052","title":"MDMA-assisted therapy for posttraumatic stress disorder: A pooled analysis of ethnoracial differences in efficacy and safety from two Phase 2 open-label lead-in trials and a Phase 3 randomized, blinded placebo-controlled trial","year":2022,"lang":"en","type":"article","venue":"Journal of Psychopharmacology","topic":"Psychedelics and Drug Studies","field":"Psychology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Mississippi Association Of Professional Surveyors","keywords":"MDMA; Placebo; Randomized controlled trial; Adverse effect; Medicine; Clinical endpoint; Psychology; Psychiatry; Clinical psychology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.009190693,0.0003767618,0.005683263,0.001474753,0.0002011328,0.00006188532,0.0005835678,0.0001450984,0.0008301205],"category_scores_gemma":[0.000781558,0.0002841355,0.000540639,0.0009023572,0.0002497159,0.0001102567,0.0001150736,0.0005863868,3.041781e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006139464,"about_ca_system_score_gemma":0.0001438556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005005545,"about_ca_topic_score_gemma":0.0007117861,"domain_scores_codex":[0.9900693,0.005155035,0.003509596,0.0005156577,0.0003471276,0.0004032409],"domain_scores_gemma":[0.9845423,0.0120358,0.00292686,0.0002085817,0.0001546175,0.0001319134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9188834,0.01701617,0.0004304055,0.00001143686,0.01630315,0.00004743733,0.006708101,0.00006810665,0.003647033,0.00009066101,0.0003443248,0.03644979],"study_design_scores_gemma":[0.9806807,0.005301328,0.0008984826,0.00002714316,0.005726249,0.0000083896,0.002499328,0.003620438,0.00002099504,0.0008598087,0.0001075108,0.0002496247],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9755067,0.01252488,0.0003275141,0.001890492,0.00198178,0.007195238,0.0004547013,0.000006882185,0.0001118084],"genre_scores_gemma":[0.9961026,0.001773258,0.0002196352,0.000391986,0.0002503823,0.001179113,0.0000235381,0.00002502141,0.00003451456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06179731,"threshold_uncertainty_score":0.9999611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1380660887534042,"score_gpt":0.4949962952954799,"score_spread":0.3569302065420757,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}