{"id":"W4283212705","doi":"10.21203/rs.3.rs-1721829/v1","title":"Signet Ring Cell Colorectal Cancers portend an aggressive biology: A 17-year analysis of operable colorectal cancers at a tertiary hospital in Pakistan","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Colorectal Cancer Screening and Detection","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Hospital","funders":"","keywords":"Signet ring cell; Colorectal cancer; Medicine; Signet ring cell carcinoma; Histopathology; Rectum; Internal medicine; Adenocarcinoma; Gastroenterology; Cancer; Population; Carcinoma; Oncology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003519028,0.0002995629,0.0003201551,0.001153835,0.001146602,0.0007863303,0.0003753889,0.0004292721,0.001706651],"category_scores_gemma":[0.0008686809,0.0004497036,0.0003977079,0.001329247,0.0005252858,0.0007204136,0.0007884668,0.0005575386,0.0003670709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007891629,"about_ca_system_score_gemma":0.0009976084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01297067,"about_ca_topic_score_gemma":0.01443727,"domain_scores_codex":[0.9995385,0.00005063346,0.00005456139,0.0001138677,0.00009629128,0.0001460786],"domain_scores_gemma":[0.9989181,0.0001098283,0.0004678863,0.00005185313,0.0001478616,0.0003044728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0000190946,0.00001821668,0.9988153,0.000004583097,0.000007890159,0.0004864625,0.0001336261,0.000008187381,0.0001359074,0.000004282113,0.00004211917,0.0003243085],"study_design_scores_gemma":[0.000002166774,0.00008007964,0.9973767,0.000005187788,0.000009751269,0.001162332,0.001150146,0.0000524601,0.00004310611,0.000005194035,0.0001090139,0.00000378323],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996462,0.00004306934,0.00002033858,0.00002892057,0.000002263148,0.000005330893,0.0001329051,9.528196e-7,0.0001200608],"genre_scores_gemma":[0.9996223,0.00007360622,0.0000262413,0.00002256817,0.000006543786,0.000003146109,0.0001729719,6.346814e-7,0.00007180719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01297067,"threshold_uncertainty_score":0.02579039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0284342365836545,"score_gpt":0.3869576410965441,"score_spread":0.3585234045128896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}