{"id":"W4283258125","doi":"10.1007/s10787-022-01013-y","title":"The Biota orientalis, oil extract Epiitalis®, is efficacious at reducing the symptoms of knee osteoarthritis: a pilot, multi-site, dose-ranging, randomized, blinded, placebo-controlled trial","year":2022,"lang":"en","type":"article","venue":"Inflammopharmacology","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Osteoarthritis; Placebo; Visual analogue scale; Population; Randomized controlled trial; Dose-ranging study; Brief Pain Inventory; Confidence interval; Physical therapy; Anesthesia; Internal medicine; Chronic pain; Double blind","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001028369,0.001164495,0.001747033,0.000397677,0.0003591183,0.0007009021,0.0006160593,0.001143469,0.005346313],"category_scores_gemma":[0.0007982152,0.0004585454,0.0009616934,0.0003268942,0.0006883086,0.0005314421,0.0002983172,0.001473664,0.0006751109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002763491,"about_ca_system_score_gemma":0.0005595925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005268709,"about_ca_topic_score_gemma":0.001452357,"domain_scores_codex":[0.9996624,0.0001756774,0.00002979939,0.00005769028,0.00003144383,0.00004300272],"domain_scores_gemma":[0.9996077,0.0001012296,0.00009341273,0.00003005984,0.00003933601,0.0001281968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9515135,0.01781493,0.0004616752,0.001087129,0.0007222058,0.00004133917,0.00004636129,0.0001294585,0.007853557,0.00004440666,0.000302773,0.01998263],"study_design_scores_gemma":[0.8077121,0.1875016,0.002596861,0.00004060699,0.0005398035,0.0000320295,0.0000264039,0.0001834919,0.0008538199,0.00003613938,0.0004664921,0.00001073688],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884255,0.004829745,0.0004855285,0.0003350279,0.0003315469,0.003308143,0.0005583386,0.00009768949,0.001628506],"genre_scores_gemma":[0.9890025,0.003348787,0.0009871162,0.0005264459,0.0003949646,0.00251604,0.0004808149,0.00001207356,0.002731386],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005346313,"threshold_uncertainty_score":0.01788527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01675574728347998,"score_gpt":0.2892840726511102,"score_spread":0.2725283253676302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}