{"id":"W4283271096","doi":"10.1111/febs.16558","title":"The intestinal immune system and gut barrier function in obesity and ageing","year":2022,"lang":"en","type":"review","venue":"FEBS Journal","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Aging","keywords":"Inflammation; Ageing; Context (archaeology); Adipose tissue; Immune system; Insulin resistance; Immunology; Pathogenesis; Obesity; Medicine; Neurodegeneration; Barrier function; Intestinal permeability; Diabetes mellitus; Biology; Disease; Pathology; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005031041,0.000849824,0.001133978,0.0018996,0.0002952739,0.0009750155,0.0006907307,0.001381461,0.00341935],"category_scores_gemma":[0.0006653648,0.000229083,0.0003884264,0.001724684,0.0004078926,0.001241416,0.0007983689,0.001855432,0.002450723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000597954,"about_ca_system_score_gemma":0.0008892874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007552469,"about_ca_topic_score_gemma":0.001301947,"domain_scores_codex":[0.9998401,0.00002898517,0.00002468884,0.0000240444,0.00006214237,0.00001999382],"domain_scores_gemma":[0.999755,0.0000936637,0.00003575887,0.000008053395,0.0000687657,0.0000388325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000104623,0.00005665832,0.0002177408,0.0133601,0.00007989426,0.00028838,0.0000645502,0.0002902972,0.002461487,0.0036552,0.04423209,0.9351889],"study_design_scores_gemma":[0.00001123131,0.00008393501,0.001171521,0.002555991,0.00007484369,0.001511325,0.00005338497,0.00006462601,0.0003925634,0.001720148,0.9923447,0.00001580341],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009614614,0.9982261,0.0001238496,0.0003690795,0.0003899951,0.000003336323,0.00001533193,0.000009901682,0.0007662814],"genre_scores_gemma":[0.0006063865,0.9978594,0.0001711352,0.0002185855,0.0003059807,0.000005827345,0.00003106967,0.000001715952,0.0007998267],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00341935,"threshold_uncertainty_score":0.01143885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02042351021908093,"score_gpt":0.2816233651947728,"score_spread":0.2611998549756919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}