{"id":"W4283311979","doi":"10.1016/j.cjca.2022.06.013","title":"PCSK9 Inhibition Following Myocardial Infarction: A Right Time to Act","year":2022,"lang":"en","type":"letter","venue":"Canadian Journal of Cardiology","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"Heart and Stroke Foundation of Canada","keywords":"Medicine; Alirocumab; PCSK9; Evolocumab; Myocardial infarction; Mace; Internal medicine; Statin; Residual risk; Acute coronary syndrome; Randomized controlled trial; Adverse effect; Cardiology; Cholesterol; Lipoprotein; Percutaneous coronary intervention; LDL receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002356904,0.00105906,0.00254701,0.0008964117,0.004501855,0.005240909,0.001789014,0.06471422,0.008123518],"category_scores_gemma":[0.01848909,0.0006175528,0.002351866,0.0006861123,0.003161319,0.004499153,0.001837873,0.05192814,0.006891599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005543954,"about_ca_system_score_gemma":0.006310285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007645454,"about_ca_topic_score_gemma":0.01808064,"domain_scores_codex":[0.9974253,0.0006031304,0.0003701581,0.0002842839,0.0007968838,0.0005202533],"domain_scores_gemma":[0.9925973,0.002932056,0.0004918431,0.0002055809,0.0009711727,0.002801856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002159302,0.0001829611,0.001154094,0.00008934855,0.0000563077,0.007346206,0.0001485862,0.0001367688,0.0003318516,0.002923496,0.9617055,0.02570893],"study_design_scores_gemma":[0.000864114,0.0005606777,0.004933699,0.001908365,0.0001645316,0.01189703,0.001352274,0.001048561,0.0003653667,0.0249084,0.9517601,0.0002366913],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0004595915,0.002587942,0.0001134282,0.9785889,0.01469584,0.00001159719,0.00002481827,0.0000329478,0.003484918],"genre_scores_gemma":[0.005712207,0.003024316,0.0004317371,0.9090111,0.07687454,0.00003394634,0.00003491452,0.00002258994,0.004854725],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.06471422,"threshold_uncertainty_score":0.04022431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0101339245535472,"score_gpt":0.2254865833676719,"score_spread":0.2153526588141247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}