{"id":"W4283325036","doi":"10.1093/genetics/iyac093","title":"Interactions of<i>Caenorhabditis elegans</i>β-tubulins with the microtubule inhibitor and anthelmintic drug albendazole","year":2022,"lang":"en","type":"article","venue":"Genetics","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; University of Waterloo","keywords":"Anthelmintic; Caenorhabditis elegans; Biology; Albendazole; Microtubule; Genetics; Drug; Caenorhabditis; Pharmacology; Gene; Zoology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006811968,0.0003905126,0.0002151112,0.0001716336,0.0002069502,0.0002404947,0.0003753914,0.0003368216,0.0007759232],"category_scores_gemma":[0.00009494831,0.0002085553,0.0002794005,0.00008466785,0.0001930279,0.0001142814,0.0002161259,0.0004854198,0.0001985574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005530785,"about_ca_system_score_gemma":0.0002194151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005600989,"about_ca_topic_score_gemma":0.008815859,"domain_scores_codex":[0.9998271,0.00001375097,0.00001317574,0.00003792241,0.00006743086,0.00004054471],"domain_scores_gemma":[0.9999218,0.000007840907,0.00002719742,0.000006364061,0.00001120775,0.00002564215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003528979,0.00001272131,0.0001978899,0.0000217267,0.000004185956,0.00003884144,0.000004007346,0.00005657554,0.9992261,0.00002715223,0.00004832522,0.0003271425],"study_design_scores_gemma":[0.00002253792,0.0002474496,0.02333105,0.00002172057,0.00003017789,0.0003160838,0.00005433974,0.003515526,0.9673611,0.00005656531,0.005025756,0.00001780446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945806,0.001283781,0.0008627029,0.0001823073,0.00005662729,0.00002800707,0.0004483137,0.0001058099,0.002451724],"genre_scores_gemma":[0.9945959,0.0006306237,0.00130595,0.0001395547,0.000007417607,0.0000276979,0.000373851,0.00002411287,0.002894776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005600989,"threshold_uncertainty_score":0.01113677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004021217187888096,"score_gpt":0.1964709131988182,"score_spread":0.1924496960109301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}