{"id":"W4283326836","doi":"10.3389/fmicb.2022.922887","title":"HIV Pre-exposure Prophylaxis and Its Impact on the Gut Microbiome in Men Having Sex With Men","year":2022,"lang":"en","type":"review","venue":"Frontiers in Microbiology","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Microbiome; Men who have sex with men; Pre-exposure prophylaxis; Medicine; Population; Human immunodeficiency virus (HIV); Gut flora; Randomized controlled trial; Immunology; Bioinformatics; Biology; Environmental health; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001059937,0.0002493663,0.0009590115,0.002326954,0.0003361835,0.0009706962,0.0002023196,0.0006127902,0.003186554],"category_scores_gemma":[0.005504414,0.0001663326,0.001286233,0.003330331,0.0002465157,0.0008588683,0.0005958391,0.0004513126,0.0001826483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003134401,"about_ca_system_score_gemma":0.00131798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002920945,"about_ca_topic_score_gemma":0.00833443,"domain_scores_codex":[0.999126,0.0003705546,0.000259677,0.0000806839,0.0001206988,0.00004245321],"domain_scores_gemma":[0.9971718,0.001908918,0.0006425076,0.00004405603,0.0001579104,0.0000748153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001600902,0.0001192232,0.07243153,0.3428074,0.005238787,0.0007707078,0.002713795,0.0001843394,0.001824716,0.0009450504,0.007942849,0.5634207],"study_design_scores_gemma":[0.0002550214,0.001547798,0.5041883,0.3100727,0.0259687,0.00465085,0.004250232,0.0002311472,0.001335614,0.00229583,0.1450718,0.0001321339],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01827426,0.97859,0.00008598583,0.00119715,0.0001389197,0.0000315216,0.0008248891,0.000005519946,0.0008519351],"genre_scores_gemma":[0.09701457,0.8998868,0.0007592826,0.001208639,0.0002401376,0.00006865427,0.0005169024,0.00000463265,0.0003003976],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003186554,"threshold_uncertainty_score":0.01066011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01935486643810155,"score_gpt":0.3273498979049819,"score_spread":0.3079950314668803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}