{"id":"W4283330500","doi":"10.1016/j.jbc.2022.102180","title":"DEAD box 1 (DDX1) protein binds to and protects cytoplasmic stress response mRNAs in cells exposed to oxidative stress","year":2022,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Oxidative stress; Cytoplasm; Cell biology; DEAD box; Unfolded protein response; Fight-or-flight response; Biology; Biochemistry; RNA; Gene; Endoplasmic reticulum","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000131526,0.0003038351,0.0004264261,0.0001766707,0.000204843,0.0002975536,0.0001516595,0.0002869468,0.001280217],"category_scores_gemma":[0.00009652176,0.0001779083,0.0002008905,0.0001426457,0.0002004056,0.0002052212,0.0002684442,0.0004576209,0.0003851608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001774148,"about_ca_system_score_gemma":0.00009031862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000189479,"about_ca_topic_score_gemma":0.0002587837,"domain_scores_codex":[0.9998851,0.00001179438,0.00001073636,0.00004280525,0.00002744965,0.00002215997],"domain_scores_gemma":[0.9998809,0.00002201778,0.00003827746,0.00001518672,0.00001329116,0.00003028383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005997522,0.000006669984,0.0001488053,0.00003093942,0.000003097618,0.00002031655,0.00001150264,0.00001092117,0.9992874,0.00001964164,0.00002194527,0.0003787829],"study_design_scores_gemma":[0.00001013058,0.0001547077,0.01695641,0.000007835538,0.00001088664,0.0002430689,0.00004387677,0.0004040688,0.9800121,0.00005377555,0.002098114,0.000004986683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897724,0.003984491,0.004617575,0.0001427247,0.0000746279,0.00001506112,0.0006436558,0.0001075683,0.0006419951],"genre_scores_gemma":[0.9907952,0.001652964,0.002386138,0.0001120232,0.00002201766,0.00003230801,0.001474168,0.00003178596,0.003493499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001280217,"threshold_uncertainty_score":0.004282773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01823017415966799,"score_gpt":0.2681876680841315,"score_spread":0.2499574939244635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}