{"id":"W4283331887","doi":"10.1097/01.hs9.0000843912.35755.7f","title":"S255: EFFICACY AND SAFETY OF TISAGENLECLEUCEL IN PEDIATRIC AND YOUNG ADULT PATIENTS (PTS) WITH RELAPSED OR REFRACTORY (R/R) MATURE B-CELL NON-HODGKIN LYMPHOMA (NHL): THE PHASE II BIANCA STUDY","year":2022,"lang":"en","type":"article","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Fludarabine; Internal medicine; Phases of clinical research; Lymphoma; Clinical endpoint; Refractory (planetary science); Oncology; Cyclophosphamide; Gastroenterology; Surgery; Chemotherapy; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006628582,0.0004884921,0.0007778436,0.0001794044,0.0001996185,0.0006079815,0.0004496713,0.0005489397,0.004384617],"category_scores_gemma":[0.0003924095,0.0001613888,0.0003730306,0.0001828888,0.0004010863,0.0004034456,0.0002449296,0.001031959,0.0008577176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005410861,"about_ca_system_score_gemma":0.0008747431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007437291,"about_ca_topic_score_gemma":0.001955606,"domain_scores_codex":[0.9998241,0.00008216064,0.00001326606,0.00002824778,0.00002344161,0.00002883373],"domain_scores_gemma":[0.9997767,0.0000260679,0.00005087678,0.00001039032,0.00001243873,0.0001236328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6499066,0.03345598,0.01601792,0.001630174,0.001417653,0.0005873956,0.0003465459,0.003439142,0.08075123,0.0008080488,0.00901533,0.202624],"study_design_scores_gemma":[0.3122383,0.6248744,0.03412439,0.0001161032,0.0006933525,0.001034235,0.000124662,0.002422539,0.01195341,0.0002598208,0.01210946,0.00004932486],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945087,0.002096672,0.0001608061,0.0002245616,0.00004741239,0.0005077338,0.0007168448,0.00006473908,0.001672586],"genre_scores_gemma":[0.9947431,0.0008685446,0.0004521295,0.0003483727,0.00004770522,0.0003785055,0.001538962,0.00001137478,0.001611351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004384617,"threshold_uncertainty_score":0.01466799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01166383156354024,"score_gpt":0.2766023768999559,"score_spread":0.2649385453364157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}