{"id":"W4283362890","doi":"10.3390/vaccines10071004","title":"A Cloned Recombinant Vesicular Stomatitis Virus-Vectored Marburg Vaccine, PHV01, Protects Guinea Pigs from Lethal Marburg Virus Disease","year":2022,"lang":"en","type":"article","venue":"Vaccines","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada","funders":"Biomedical Advanced Research and Development Authority; Public Health Agency of Canada","keywords":"Filoviridae; Marburg virus; Virology; Vesicular stomatitis virus; Vesicular Stomatitis; Ebola virus; Biology; Ebola vaccine; Virus; Ebolavirus; Vesicular stomatitis Indiana virus; Viral disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002538077,0.0004043601,0.0002755336,0.0001767767,0.00008153822,0.0002185167,0.0002868631,0.0005498357,0.0008068767],"category_scores_gemma":[0.0001786729,0.000107452,0.000229066,0.00006938812,0.0002272405,0.0002211672,0.0001561355,0.0006949764,0.0002190054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002046614,"about_ca_system_score_gemma":0.0002074659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002624602,"about_ca_topic_score_gemma":0.0003887733,"domain_scores_codex":[0.9998775,0.00003529058,0.000009092667,0.00002871792,0.00002082551,0.00002859516],"domain_scores_gemma":[0.9999268,0.00002549751,0.00001659445,0.000009924228,0.000007845643,0.00001332977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001119529,0.0001127362,0.000279516,0.00004785107,0.000006129354,0.00005386812,0.00001172831,0.0001189113,0.997422,0.00009691843,0.00002972424,0.001708683],"study_design_scores_gemma":[0.00009475042,0.005868423,0.004040264,0.0000200709,0.00003224649,0.0004976831,0.00003224877,0.001161924,0.9859443,0.00006447949,0.002236914,0.000006729876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932019,0.0006448195,0.004914089,0.0001153898,0.00005205908,0.0001284146,0.0002767667,0.00005694787,0.0006096876],"genre_scores_gemma":[0.9910131,0.0006163908,0.006328006,0.0000720661,0.00001597903,0.00008556192,0.000728578,0.0000101438,0.00113013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008068767,"threshold_uncertainty_score":0.002699256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01750926807325616,"score_gpt":0.2758506966241412,"score_spread":0.258341428550885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}