{"id":"W4283368050","doi":"10.1101/2022.06.16.22276291","title":"Peripheral Blood Gene Expression at 3 to 24 Hours Correlates with and Predicts 90-Day Outcome Following Human Ischemic Stroke","year":2022,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; National Institutes of Health; Heart and Stroke Foundation of Canada; National Institute of Neurological Disorders and Stroke; American Heart Association","keywords":"Modified Rankin Scale; Medicine; Stroke (engine); Internal medicine; Gene expression; Immune system; Gene; Bioinformatics; Oncology; Immunology; Ischemic stroke; Biology; Ischemia; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001458889,0.0001789551,0.0003945136,0.0003423919,0.0001260559,0.0003236579,0.00006405347,0.0001613092,0.0008413065],"category_scores_gemma":[0.0002910494,0.00007173327,0.0001941087,0.0004749145,0.0001019042,0.0001073817,0.0001611023,0.000176403,0.000214535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001361835,"about_ca_system_score_gemma":0.0001128478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008733884,"about_ca_topic_score_gemma":0.001272979,"domain_scores_codex":[0.99991,0.00001562868,0.000004866983,0.000035147,0.00001410507,0.00002024072],"domain_scores_gemma":[0.9998581,0.00002764568,0.00005820279,0.00001021319,0.00002416866,0.00002159146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005761938,0.000224594,0.8865057,0.0001768867,0.0004063232,0.0002146765,0.0001620506,0.002564721,0.07446191,0.0001013324,0.001264946,0.02815498],"study_design_scores_gemma":[0.00001424094,0.00024571,0.9950152,0.000008381788,0.00006128081,0.0001017107,0.00006613958,0.002091799,0.001997568,0.0001373553,0.0002550019,0.000005625452],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977315,0.0003746129,0.0003354903,0.00002403707,0.000006257499,0.000007536397,0.001226305,0.00001143156,0.0002828017],"genre_scores_gemma":[0.9973403,0.0002154746,0.0002487582,0.00002326322,0.000007939701,0.00001650191,0.001830538,0.000002917748,0.0003143178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008733884,"threshold_uncertainty_score":0.002814472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03710515850976769,"score_gpt":0.2732262122370208,"score_spread":0.2361210537272531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}