{"id":"W4283387520","doi":"10.3390/metabo12070572","title":"Trans- and Multigenerational Maternal Social Isolation Stress Programs the Blood Plasma Metabolome in the F3 Generation","year":2022,"lang":"en","type":"article","venue":"Metabolites","topic":"Birth, Development, and Health","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Lethbridge","keywords":"Offspring; Creatine; Metabolomics; Metabolome; Taurine; Biology; Endocrinology; Internal medicine; Medicine; Biochemistry; Bioinformatics; Pregnancy; Amino acid; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001408872,0.0004647497,0.000280749,0.0003644341,0.0002585188,0.0003085842,0.0001915224,0.0002689096,0.001894003],"category_scores_gemma":[0.0002056908,0.0001498337,0.0003171376,0.0001109416,0.0003319188,0.0001890502,0.0005049403,0.0008896493,0.0001595347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002668213,"about_ca_system_score_gemma":0.0002356653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002066273,"about_ca_topic_score_gemma":0.003918449,"domain_scores_codex":[0.9998604,0.00001553616,0.000006527317,0.00005323492,0.00003065894,0.00003360733],"domain_scores_gemma":[0.9996889,0.00002617723,0.0001032497,0.00003319527,0.0000371381,0.0001114442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006104345,0.0001217531,0.008117274,0.00002827896,0.00004913576,0.0001949102,0.0001874165,0.00005235516,0.9847574,0.000114872,0.0001080581,0.00565793],"study_design_scores_gemma":[0.00005120663,0.002912659,0.6060166,0.00004476756,0.0002762629,0.0009609858,0.0008602425,0.001463457,0.3827673,0.0003970408,0.004170073,0.00007931273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980671,0.0001531214,0.001072465,0.00004534477,0.00001561017,0.000008851895,0.0002947866,0.00003280532,0.000309919],"genre_scores_gemma":[0.9947556,0.00021992,0.001261006,0.0000988577,0.0000103421,0.00006019129,0.0005357814,0.00005067068,0.003007634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002066273,"threshold_uncertainty_score":0.006336033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03791319001057967,"score_gpt":0.2839832579642458,"score_spread":0.2460700679536662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}